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Overactive Bladder (OAB)

Overactive Bladder

UroToday's Overactive Bladder section is a repository of the clinical publications, clinical trials and investigative science pertaining to the diagnosis and treatment of overactive bladder. Also available are conference coverage for all timely overactive bladder science, audio podcasts and downloadable slides from UroToday's slide library.

Online Urology & Urologic Oncology Journal
Please read about the UroToday International Journal; We welcome submissions year round and are committed to providing fast-tracked, peer reviewed publication.
Kind regards,
Christian Gratzke, MD
Associate Section Editor Overactive Bladder
UroToday International Journal

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Urgent® PC and Macroplastique® featured in numerous International Continence Society meeting sessions
Tuesday, 06 October 2009
MINNEAPOLIS, MN, USA (Press Release) - October 6, 2009
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Beyond the Abstract - A systematic evaluation of factors associated with nocturia--The population-based FINNO Study, by Kari A.O. Tikkinen, Jeffrey P. Weiss and Theodore M. Johnson, II
Tuesday, 06 October 2009
BERKELEY, CA (UroToday.com) - Using the population-based FINNO Study group, we sought to identify major risk factors for nocturia.
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ICS 2009 - The effect of acute and chronic stress and anxiety-like behaviour on bladder motor and sensory function - Session Highlights
Tuesday, 06 October 2009
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ICS 2009 - Pudendal nerve stimulation is a viable alternative to sacral nerve stimulation for voiding dysfunction - Session Highlights
Tuesday, 06 October 2009
SAN FRANCISCO, CA, USA (UroToday.com) - Pudendal nerve stimulation involves the distal branch of sacral nerve with contributing fibers from S2, S3, and S4.
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AUA NY 2009 - Evidence based results from complementary and alternative medicine in urology - Multimedia Presentation
Monday, 05 October 2009
SEWARD, AK, USA - Presented by Franklin C. Lowe, MD, MPH at the 107th Annual Meeting of the AUA - New York Section - August 19 - 26, 2009, Seward, Alaska, USA
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URS 2009 - Effects of a novel peripheral selective cannabinoid-2-receptor agonist (Cannabinor) on bladder function in normal rats and rats with partial urethral obstruction - Slide Presentation
Wednesday, 30 September 2009
NORTH QUEENSLAND, AUSTRALIA (UroToday.com) - Presented by Christian Gratzke, MD at the Urological Research Society (URS) - 25th Annual Meeting - August 10 - 14, 2009
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URS 2009 - ATP release in response to acid and capsaicin provides evidence for sensory roles of vanilloid and ASIC receptor systems in the rat bladder mucosa - Slide Presentation
Wednesday, 30 September 2009
NORTH QUEENSLAND, AUSTRALIA (UroToday.com) - Presented by Elizabeth Burcher, MD at the Urological Research Society (URS) - 25th Annual Meeting - August 10 - 14, 2009
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URS 2009 - TRPV4 as a mechanoreceptor in the human bladder; A co-localization between TRPV4 and adherence junctions in the human bladder urothelium - Slide Presentation
Wednesday, 30 September 2009
NORTH QUEENSLAND, AUSTRALIA (UroToday.com) - Presented by Jack A. Schalken, MD at the Urological Research Society (URS) - 25th Annual Meeting - August 10 - 14, 2009
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Beyond the Abstract - Evaluating patient learning after an educational program for women with incontinence and pelvic organ prolapse, by Roxana Geoffrion, MD, et al.
Tuesday, 29 September 2009
BERKELEY, CA (UroToday.com) - Pelvic floor disorders such as incontinence and prolapse are common bothersome conditions that can be initially and successfully addressed with conservative patient-initiated methods such as pelvic floor muscle and bladder retraining exercises.
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Is ultrasound estimation of bladder weight a useful tool in the assessment of patients with lower urinary tract symptoms? - Abstract
Monday, 28 September 2009
Department of Urogynaecology, St. Marys Hospital, Imperial College Healthcare NHS Trust, Praed Street, London, W2 1NY, UK.
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Therapy of overactive bladder with propiverine ER : Results of a non-interventional study with a propiverine retard formulation and comparison to clinical studies - Abstract
Friday, 25 September 2009
Praxis für Urologie, Rigaer Strasse 9, 17993, Greifswald, Deutschland.
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Trospium chloride extended release is effective and well tolerated in women with overactive bladder syndrome - Abstract
Thursday, 24 September 2009
Division of Urogynecology and Reconstructive Surgery, NorthShore University HealthSystem, Pritzker School of Medicine, University of Chicago, Evanston, IL, USA.
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Editorial - Flexible and rigid cystoscopy in women
Wednesday, 23 September 2009
BERKELEY, CA (UroToday.com) - In this single blinded, prospective study, 36 women requiring cystoscopy were randomized to either rigid or flexible cystoscopy;
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Algorithms for the management of overactive bladder - Abstract
Wednesday, 23 September 2009
Division of Urology, University of Vermont, The Continence Center, FAHC, 1775 Williston Road, South Burlington, VT 05482, USA.
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Neuromodulation versus medication for overactive bladder - Abstract
Tuesday, 22 September 2009
William Beaumont Hospital, 3535 West Thirteen Mile Road, Suite 438, Royal Oak, MI 48073, USA.
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Focus on Overactive Bladder

Focus on Overactive Bladder condenses a selection of compelling and relevant science - on topic and chosen by the UroToday.com editorial staff.

Podcast - Effective Darifenacin Treatment after Dissatisfaction with Prior Extended-Release Antimuscarinic Therapy

World Continence Week 2009

Patient Guide - Controlling Your Bladder Symptoms

- Prepared by Diane K. Newman, MSN, CRNP, FAAN, BCIA-PMDM

Promoting Continence Worldwide

- Prepared by Diane K. Newman, MSN, CRNP, FAAN, BCIA-PMDM

Urinary Incontinence: Epidemiology and Disease Burden
- Prepared by Alan J. Wein, MD, PhD (hon)

Differential Pharmacological Effects of Antimuscarinic Drugs on Heart Rate: A Randomized, Placebo-Controlled, Double-Blind, Crossover Study with Tolterodine and Darifenacin in Healthy Participants > or = 50 years
- by Brian Olshansky, MD

Darifenacin Treatment for Overactive Bladder in Patients Who Expressed Dissatisfaction With Prior Extended-Release Antimuscarinic Therapy
- by Norman Zinner, MD, et al.

Suburothelial Myofibroblasts in the Human Overactive Bladder and the Effect of Botulinum Neurotoxin Type A Treatment
- by Alexander Roosen, MD and Clare J. Fowler, MD

A Systematic Review and Meta-Analysis of Randomized Controlled Trials with Antimuscarinic Drugs for Overactive Bladder
- by Giacomo Novara, MD, FEBU

Emerging Drugs for Treatment of Overactive Bladder and Detrusor Overactivity
- by Marcus Drake, MD

Two Types of Urgency
- by Philip M. Hanno, MD, MPH - Editor's Pick

Long-Term Efficacy and Safety of Tolterodine in Children with Neurogenic Detrusor Overactivity
- by Pasquale Casale, MD

Defining Overactive Bladder as Hypersensitivity
- by Philip M. Hanno, MD, MPH

Minimally Invasive Therapy for Neurogenic Detrusor Overactivity: A Review
- by Karl-Erik Andersson, Roger Dmochowski and Alan Wein

A Randomized Controlled Study of Posterior Tibial Nerve Stimulation for Overactive Bladder
- by Paula Palma, MD, PhD. et al.

Efficacy and Tolerability of Add-On Trospium Chloride in Patients with Benign Prostate Syndrome and Overactive Bladder: A Noninterventional Trial Showing Use of Flexible Dosing
- by Ulrich Schwantes, PhD, et al.

The second-line management of idiopathic overactive bladder: What is the place of sacral neuromodulation and botulinum toxin-A in contemporary practice?

On the Origins of the Sensory Output from the Bladder: The Concept of Afferent Noise

A Review of Adherence to Drug Therapy in Patients with Overactive Bladder

Sacral Neuromodulation for Treating the Symptoms of Overactive Bladder Syndrome and Non-Obstructive Urinary Retention: More Than 10 Years of Clinical Experience

Urine cytokines suggest an inflammatory response in the overactive bladder: a pilot study
- by Michael Chancellor, MD, et al.

Obesity is associated with a more severe overactive bladder disease state that is effectively treated with once-daily administration of trospium chloride extended release
- by Michael G. Oefelein, MD, et al.

Ten years single surgeon experience with botulinum toxin in the urinary tract; clinical observations and research discovery
- by Michael Chancellor, MD.

The evolution of transdermal therapy for overactive bladder
- by Peter K. Sand, MD

Outcome of a Randomized, Double-Blind, Placebo Controlled Trial of Botulinum A Toxin for Refractory Overactive Bladder
- by Michael K. Flynn, MD, et al.

InterStim Therapy: A Contemporary Approach to Overactive Bladder
- by Neeraj Kohli, MD, MBA and Danielle Patterson, MD

Differential Pharmacological Effects of Antimuscarinic Drugs on Heart Rate: A Randomized, Placebo-Controlled, Double-Blind, Crossover Study with Tolterodine and Darifenacin in Healthy Participants > or = 50 years
- by Brian Olshansky, MD, et al.

Randomized Comparison of Tolterodine With Vaginal Estrogen Cream Versus Tolterodine Alone for the Treatment of Postmenopausal Women With Overactive Bladder Syndrome
- by Ling-Hong Tseng, MD, et al.

The role of industry funding in randomized controlled trials of antimuscarinic medications for overactive bladder
- Session Highlight by Ariana L. Smith, MD from the International Continence Society (ICS) 39th Annual Meeting

State of the Art Lecture: Bladder re-innervation: Can new nerves improve the function of the neurogenic bladder?
- Session Highlight by Ariana L. Smith, MD from the International Continence Society (ICS) 39th Annual Meeting

Is ultrasound bladder wall thickness a better measure than urodynamics for overactive bladder symptoms?
- Session Highlight by Ariana L. Smith, MD from the International Continence Society (ICS) 39th Annual Meeting

Urodynamics/Incontinence/Female Urology: Urodynamic Testing - Identification of Measures of Bladder Sensation in Patients with Overactive Bladder
- Session Highlight by Kathleen Kobashi, MD from the 2009 Annual Meeting of the American Urological Association (AUA)

Session Highlights from the Society for Urodynamics & Female Urology 2009 Winter Meeting
- Exclusive Coverage by UroToday Contributing Medical Editor, William Jaffe, MD

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at The National Institutes of Health (NIH) - UI Symposium
- Session Highlights Reported by Diane K. Newman

Drug Treatment - Lecture Series

- Presented by Karl-Erik Andersson, MD, PhD, and Christopher Chapple, MD, et al. at the Fourth International Consultation on Incontinence (ICI)

Drug Treatment - Committee Meeting Highlights

- Reported by William Jaffe, MD from the Fourth International Consultation on Incontinence (ICI)

Voiding Dysfunction Session Highlights

- From the American Urological Association 2008 Annual Meeting

Urodynamics and Reality

- Presented by Ed McGuire, MD, at the 32nd Winter Urologic Forum

Clinical Proof of Concept Study (BLOSSOM) Shows Novel Beta 3 Adrenoceptor Agonist YM178 is Effective and Well Tolerated in the Treatment of Symptoms of Overactive Bladder
- Presented at the European Association of Urology - 23rd Annual EAU Congress

International Consultation on Incontinence - ICI 2008
- Session Abstracts, Overactive Bladder