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Interstitial Cystitis / Painful Bladder

Painful bladder syndrome/interstitial cystitis: Aetiology, evaluation and management - Abstract

Interstitial cystitis or bladder pain syndrome (BPS) is often a chronic debilitating condition characterised by predominantly storage symptoms and associated frequently with pelvic pain that varies with bladder filling.

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Treating interstitial cystitis/bladder pain syndrome as a chronic disease - Abstract

The management of interstitial cystitis/bladder pain syndrome (IC/BPS) is both frustrating and difficult.

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Mast cell activation and response to tolterodine in the rat urinary bladder in a chronic model of intravesical protamine sulfate and bacterial endotoxin-induced cystitis - Abstract

The aim of the present study was to use an animal model of interstitial cystitis (IC) in order to investigate the histology and function of the bladder, with a particular focus on mast cell degranulation and response to detrusor overactivity (DO) to tolterodine.

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Polyomavirus BK - A potential new therapeutic target for painful bladder syndrome/interstitial cystitis? - Abstract

AIMS: To investigate the role of urinary BK polyoma virus (BKPyV) in the pathophysiology and prognosis of patients with painful bladder syndrome/interstitial cystitis (PBS/IC).

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Intravesical TRPV4 blockade reduces repeated variate stress (RVS)-induced bladder dysfunction by increasing bladder capacity and decreasing voiding frequency - Abstract

Individuals with functional lower urinary tract disorders including interstitial cystitis (IC)/bladder pain syndrome (BPS) and overactive bladder (OAB) often report symptom worsening due to stress.

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Evidence for bladder urothelial pathophysiology in functional bladder disorders - Abstract

Understanding of the role of urothelium in regulating bladder function is continuing to evolve.

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Correlation of gene expression with bladder capacity in interstitial cystitis/bladder pain syndrome - Abstract

PURPOSE: Interstitial cystitis and bladder pain syndrome (IC/BPS) are terms used to describe a heterogeneous chronic pelvic and bladder pain disorder.

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Chemical cystitis developed in experimental animals model: Topical effect of intravesical ozone application to bladder - Abstract

AIMS: To demonstrate the effects of intravesical ozone treatment on inflammation and epithelial cell damage in chemical cystitis animal model.

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Examination of the significant placebo effect in the treatment of interstitial cystitis/bladder pain syndrome - Abstract

OBJECTIVE: To examine the significant "placebo effect" in a randomized, double-blind, placebo-controlled interstitial cystitis/bladder pain syndrome trial.

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Effect of inflammatory mediators on ATP release of human urothelial RT4 cells - Abstract

Inflammation is an important contributor to the aetiology of a number of bladder dysfunctions including interstitial cystitis, painful bladder syndrome, and overactive bladder.

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