Prostate Cancer

Transrectal real-time tissue elastography - an effective way to distinguish benign and malignant prostate tumors - Abstract

Background: To investigate the relationship between extracellular matrix parameters and texture of prostatic lesions evaluated by transrectal real-time tissue elastography (TRTE).

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Improving sexual health in men with prostate cancer: Randomised controlled trial of exercise and psychosexual therapies - Abstract

BACKGROUND: Despite being a critical survivorship care issue, there is a clear gap in current knowledge of the optimal treatment of sexual dysfunction in men with prostate cancer.

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Carboxypeptidase-D is elevated in prostate cancer and its anti-apoptotic activity is abolished by combined androgen and prolactin receptor targeting - Abstract

BACKGROUND: Carboxypeptidase-D (CPD) cleaves C-terminal arginine for nitric oxide (NO) production.

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Improving the biodistribution of PSMA-targeting tracers with a highly negatively charged linker - Abstract

BACKGROUND: Prostate specific membrane antigen (PSMA) is overexpressed in prostate cancer and in tumor vasculature.

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CD44 variant 6 is associated with prostate cancer metastasis and chemo-/radioresistance - Abstract

INTRODUCTION: Prostate cancer (CaP) is the second leading malignancy in older men in Western countries.

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Nestin regulates prostate cancer cell invasion by influencing FAK and integrin localisation and functions - Abstract

Nestin, an intermediate filament protein and marker of undifferentiated cells is expressed in several cancers.

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Identification of miR-133b and RB1CC1 as independent predictors for biochemical recurrence and potential therapeutic targets for prostate cancer - Abstract

OBJECTIVE: We aimed to investigate the contribution of microRNA-133b (miR-133b) in prostate cancer cell proliferation, cell cycle, and apoptosis.

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Inhibition of CYP17A1 activity by resveratrol, piceatannol, and synthetic resveratrol analogs - Abstract

BACKGROUND: Resveratrol (RSV) and resveratrol analogs have a potential use in prostate cancer chemoprevention due to effects on for example, cell growth, apoptosis, angiogenesis, and metastasis.

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Genomic analysis in active surveillance: Predicting high-risk disease using tissue biomarkers - Abstract

PURPOSE OF REVIEW: For patients newly diagnosed with prostate cancer, the most significant question is whether the 'truly malignant' disease has been identified.

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Biomarkers in prostate cancer: What's new? - Abstract

PURPOSE OF REVIEW: This review is intended to provide an overview of the current state of biomarkers for prostate cancer (PCa), with a focus on biomarkers approved by the US Food and Drug Administration (FDA) as well as biomarkers available from Clinical Laboratory Improvement Amendment (CLIA)-certified clinical laboratories within the last 1-2 years.

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