IMPORTANCE: Surgical innovations disseminate in the absence of coordinated systems to ensure their safe integration into clinical practice, potentially exposing patients to increased risk for medical error.
As prostate cancer progresses to the lethal castration resistant and metastatic form, genetic and epigenetic adaptation, clonal selection, and evolution of the tumor microenvironment contribute to the emergence of unique biologic characteristics under the selective pressure of external stresses.
BERKELEY, CA (UroToday.com) - Identification of the optimal timing of antimicrobial prophylaxis has been extensively studied.[1, 2] The use of perioperative antimicrobial prophylaxis helps prevent surgical site infections. However, little attention has been devoted to the overuse of antibiotics and compliance with established antimicrobial prophylaxis guidelines.