Prostate Cancer

Nanoparticles of star-like copolymer mannitol-functionalized poly(lactide)-vitamin E TPGS for delivery of paclitaxel to prostate cancer cells - Abstract

The purpose of this research was to develop novel nanoparticles (NPs) of star-like copolymer mannitol-functionalized poly(lactide)-vitamin E TPGS (M-PLA-TPGS) for paclitaxel delivery for prostate cancer treatment, and evaluate their therapeutic effects in prostate cancer cell line and animal model in comparison with the linear PLGA NPs and poly(lactide)-vitamin E TPGS (PLA-TPGS) NPs.

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Genetic variants reflecting higher vitamin E status in men are associated with reduced risk of prostate cancer - Abstract

Vitamin E (α-tocopherol) plays a key role in the regulation of cell growth and differentiation and has been studied as a potential chemopreventive agent for prostate cancer.

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Predicting the risk of non-organ-confined prostate cancer when perineural invasion is found on biopsy - Abstract

OBJECTIVE: To more precisely define the risk of non-organ-confined (non-OC) prostate cancer among men with perineural invasion (PNI) identified on prostate biopsy.

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Active surveillance for low-risk prostate cancer: Diversity of practice across Europe - Abstract

BACKGROUND: Active surveillance (AS) is a recognised treatment option for low-risk prostate cancer (PCa).

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Prostate-specific antigen measured 3 months after radical prostatectomy as a new predictor of biochemical recurrence - Abstract

BACKGROUND: This study was undertaken to investigate if the prostate-specific antigen (PSA) level measured 3 months after radical prostatectomy (RP) is a predictor of biochemical recurrence (BCR)-free survival.

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Are active surveillance criteria sufficient for predicting advanced stage prostate cancer patients? - Abstract

OBJECTIVES: To examine the treatment outcomes of the prostate cancer (PCa) patients treated by radical prostatectomy (RP) who could be good candidates for active surveillance (AS) and test the confidence and reliability of the AS criterias for predicting advanced stage disease (RP Gleason score≥7 or Pathological stage T3).

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Clinical outcomes of CyberKnife radiotherapy in prostate cancer patients: Short-term, single-center experience - Abstract

PURPOSE: In this retrospective study, we analyzed the outcomes of prostate cancer patients treated with the CyberKnife radiotherapy system (Accuray).

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Radical prostatectomy as radical cure of prostate cancer in a high-risk group: A single-institution experience - Abstract

This study aimed to evaluate the possibility of performing radical prostatectomy (RP) alone to achieve radical cure of prostate cancer in a high-risk group.

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Relationship between sexual function and prostate-specific antigen bounce after iodine-125 permanent implant brachytherapy for localized prostate cancer - Abstract

OBJECTIVE: To analyze clinical and dosimetric factors involved in prostate-specific antigen bounce in patients who underwent permanent implant brachytherapy for localized prostate cancer, and to study the relationships among prostate-specific antigen bounce, age and sexual function.

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