Investigative Urology

Antiproliferative effects of zinc-citrate compound on hormone refractory prostate cancer - Abstract

Published on Tuesday, 07 May 2013 15:39

OBJECTIVE: To investigate the antiproliferative effects of zinc-citrate compound on hormone refractory prostate cancer (HRPC).

Identification of transcription factors associated with castration-resistance: Is the serum responsive factor a potential therapeutic target? - Abstract

Published on Tuesday, 07 May 2013 15:33

BACKGROUND: Advanced prostate cancer is treated by hormone ablation therapy.

Apigenin inhibits TGF-β-induced VEGF expression in human prostate carcinoma cells via a Smad2/3- and Src-dependent mechanism - Abstract

Published on Tuesday, 07 May 2013 15:28

Cancer progression relies on establishment of the blood supply necessary for tumor growth and ultimately metastasis.

Genome-wide association study identifies ioci at ATF7IP and KLK2 associated with percentage of circulating free PSA - Abstract

Published on Tuesday, 07 May 2013 15:22

BACKGROUND: Percentage of free-to-total prostate-specific antigen (%fPSA) is an independent predictor of risk for prostate cancer among men with modestly elevated level of total PSA (tPSA) in blood.

Anacardic acid (6-pentadecylsalicylic acid) induces apoptosis of prostate cancer cells through inhibition of androgen receptor and activation of p53 signaling - Abstract

Published on Tuesday, 07 May 2013 13:27

Anacardic acid (AA) is a mixture of 2-hydroxy-6-alkylbenzoic acid homologs.

Detection of circulating tumor cells in different stages of prostate cancer - Abstract

Published on Tuesday, 07 May 2013 13:23

PURPOSE: To explore circulating tumor cell (CTCs) counts in different stages of prostate cancer (PC) in association with tumor burden, metastatic pattern and conventional serum biomarkers.

Concurrent AURKA and MYCN gene amplifications are harbingers of lethal treatment-related neuroendocrine prostate cancer - Abstract

Published on Tuesday, 07 May 2013 13:05

Neuroendocrine prostate cancer (NEPC), also referred to as anaplastic prostate cancer, is a lethal tumor that most commonly arises in late stages of prostate adenocarcinoma (PCA) with predilection to metastasize to visceral organs.

A novel model of urinary tract differentiation, tissue regeneration, and disease: Reprogramming human prostate and bladder cells into induced pluripotent stem cells - Abstract

Published on Tuesday, 07 May 2013 13:00

BACKGROUND: Primary culture and animal and cell-line models of prostate and bladder development have limitations in describing human biology, and novel strategies that describe the full spectrum of differentiation from foetal through to ageing tissue are required.

Inhibition of protein kinase CK2 reduces CYP24A1 expression and enhances 1,25-dihydroxyvitamin D3 anti-tumor activity in human prostate cancer cells - Abstract

Published on Monday, 06 May 2013 13:54

Vitamin D has broad range of physiological functions and antitumor effects.

Role of CEACAM1 and CEACAM20 in an in vitro model of prostate morphogenesis - Abstract

Published on Monday, 06 May 2013 13:45

CEACAM20, a novel member of the CEACAM1 gene family with expression limited to the lumen of small intestine, testes, and prostate, is co-expressed with CEACAM1 in adult prostate tissue and down-regulated to the same extent as CEACAM1 in prostate cancer.

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