Investigative Urology

Novel Hsp90 inhibitor NVP-AUY922 radiosensitizes prostate cancer cells - Abstract

Published on Monday, 06 May 2013 13:41

Outcomes for poor-risk localized prostate cancers treated with radiation are still insufficient.

Expression of osteoprotegerin from a replicating adenovirus inhibits the progression of prostate cancer bone metastases in a murine model - Abstract

Published on Monday, 06 May 2013 13:26

Metastatic involvement of the skeleton is a frequent consequence of advanced prostate cancer.

Truncated ERG proteins affect the aggressiveness of prostate cancer - Abstract

Published on Monday, 06 May 2013 13:23

Prostate cancer is a significant health problem around the world.

A molecular complex of bovine milk protein and oleic acid selectively kills cancer cells in vitro and inhibits tumour growth in an orthotopic rat bladder tumour model - Abstract

Published on Monday, 06 May 2013 13:20

Novel intravesical therapies are needed for superficial bladder cancer that reduce the risk of infection associated with Bacillus Calmette-Guérin (BCG) and further destabilization of the urothelium associated with cytotoxic chemotherapy.

β4 Integrin signaling induces expansion of prostate tumor progenitors - Abstract

Published on Monday, 06 May 2013 08:58

The contextual signals that regulate the expansion of prostate tumor progenitor cells are poorly defined.

Behavioral stress accelerates prostate cancer development in mice - Abstract

Published on Monday, 06 May 2013 08:54

Prostate cancer patients have increased levels of stress and anxiety.

Targeting IGF-IR with ganitumab inhibits tumorigenesis and increases durability of response to androgen-deprivation therapy in VCaP prostate cancer xenografts - Abstract

Published on Monday, 06 May 2013 08:48

Prostate cancer is the most commonly diagnosed malignancy in men.

Silencing mutated β-catenin inhibits cell proliferation and stimulates apoptosis in the adrenocortical cancer cell line H295R - Abstract

Published on Monday, 06 May 2013 06:57

CONTEXT: Adrenocortical carcinoma (ACC) is a rare and highly aggressive endocrine neoplasm, with limited therapeutic options.

Establishment and characterization of the first pediatric adrenocortical carcinoma xenograft model identifies topotecan as a potential chemotherapeutic agent - Abstract

Published on Monday, 06 May 2013 06:50

PURPOSE: Pediatric adrenocortical carcinoma (ACC) is a rare and highly aggressive malignancy.

Association of GSTT1 gene polymorphisms with the risk of prostate cancer: An updating meta-analysis - Abstract

Published on Friday, 03 May 2013 15:15

It has been demonstrated that the glutathione S-transferase (GST) superfamily helps remove carcinogens from the body and thus might be associated with prostate cancer risk.

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