BERKELEY, CA (UroToday.com) - The studies reviewed in this manuscript illustrate the heterogeneity within the literature in regards to seasonal variations of testosterone.
A search for a hormonal fountain of youth has been hotly pursued over the last century, predominately by those who wish to market hormones to a gullible public.
Aging in men is associated with a decrease in serum testosterone levels due to attrition in testicular Leydig cells and slowing of the hypothalamic GnRH pulse generator.
The decline in testosterone levels found in men with testosterone deficiency syndrome (TDS) is associated with a decrease in bone mineral density (BMD).