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Tuesday, 16 May 2006 |
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- The most helpful laboratory guide for rapid diagnosis is careful microscopic examination of the urine.
- Documentation by urine culture can be helpful in diagnosing a first infection or evaluating patients with recurrent symptoms unresponsive to empirical therapy
- If hematuria is noted, the physician is obligated to be sure that it is no longer present after treatment of infection. If it is still present, a urologic imaging study and cystoscopy are necessary to rule out other urologic pathology
- If a complicated UTI is suspected by history, a similar evaluation may be necessary after the infection has cleared.
- Uncomplicated Cystitis
- Urologic investigation in not routinely indicated
- Diagnosis is often empiric, however, a urinalysis and/or culture can provide helpful documentation of the true diagnosis and causative organism
- Caveats
- Normal vaginal flora can appear to be gram-negative bacteria on urinalysis
- Pyuria may be noted in a variety of inflammatory conditions of the urinary tract
- If the patient is drinking increased fluids and voiding frequently, the urine will be dilute, and signs of infection on urinalysis may be missing
- One-third of women with acute symptomatic cystitis caused by E. coli, S. saprophyticus, or Proteus have colony counts of midstream urine specimens ranging from 102 to 104 cfu/mL. Thus, a pure culture in the presence of symptoms must be considered significant, regardless of colony count.
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