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BJUI Mini Reviews - The Discovery and Application of Gene Fusions in Prostate Cancer

This review is a summarization of the identification, characterization and detection of TMPRSS2:ETS gene fusions and their role in prostate cancer. There is also a discussion of the discovery of additional 5′partners that define distinct classes of ETS gene fusions based on the prostate specificity and androgen responsiveness of the 5′partner.


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