ANAHEIM, CA (UroToday.com) - Dr. Bret Connors from Dr. Lingeman’s group in Indiana, presented their laboratory findings when delivering 2000 shocks at 24 KV at 2 Hz (n = 9) vs 0.5 Hz (n = 11) in 6 to 8 week old juvenile pigs. The shock waves were directed at the lower pole calyx of a single kidney with an unmodified HM3 lithotripter. They found that the size of the acute parenchymal lesion was significantly less with the lower rate and that renal plasma flow fell significantly in the higher rate group. Clinical trials are awaited to determine whether this rate change translates into better or equivalent stone fragmentation and clearance rates with less chance of clinically significant renal damage.

Authors: Bret A. Connors, Andrew P. Evan, Lynn R. Willis, Rajash K. Handa, James A. McAteer, James E. Lingeman. Indianapolis, IN.

Abstract 1313

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