Long-Term Results Of Sacral Neuromodulation For Urgency-Frequency Mandate Caution
Thursday, 05 January 2006
BERKELEY, CA (UroToday.com) - Elhilali and colleagues have reported on the long term results of sacral neuromodulation therapy effectiveness in patients implanted at the McGill University Hospitals over a thirteen year period.
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Antiproliferative Factor (APF) May Contribute To The Leakiness Of The Bladder Epithelial Barrier Seen In PBS/IC
Tuesday, 03 January 2006
BERKELEY, CA (UroToday.com) - Previous reports have suggested that the bladder epithelia barrier may be compromised in PBS/IC.
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Potassium Sensitivity Test Predicts Interstitial Cystitis Treatment Response
Tuesday, 03 January 2006
NEW YORK (Reuters Health) - The potassium sensitivity test can predict the response of interstitial cystitis patients to treatment with glycosaminoglycan-substitution therapy, according to a report in the November BJU International.
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Oral Cyclosporin Proves Effective For PBS/IC In A Randomized, Comparative Study
Thursday, 22 December 2005
BERKELEY, CA (UroToday.com) - Cyclosporin in a daily divided dose of 3mg per kilogram per day was compared with sodium pentosanpolysulfate (Elmiron®) 100mg three times daily in 64 patients with PBS/IC over 6 months of treatment.
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Localization Of The Urge To Void In Patients With Painful Bladder Syndrome (PBS) Differs From Other Groups
Monday, 19 December 2005
BERKELEY, CA (UroToday.com) - The localization of the urge to void seems to involve a wider area in patients with PBS than in those with overactive bladder (OAB), stress incontinence (SI), and asymptomatic controls.
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Hydrodistention Appears To Have Limited Long-Term Benefit For Painful Bladder Syndrome / Interstitial Cystitis (PBS/IC)
Thursday, 15 December 2005
BERKELEY, CA (UroToday.com) - In a large, retrospective study of 185 patients with PBS/IC subjected to hydrodistention under general anesthesia for five minutes and then repeated after emptying for another 5 minutes, 6 month symptomatic improvement was identified in only 5%.
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Clinical Suspicion Of Perimenstrual Flare Associated With Painful Bladder Syndrome Confirmed In Trial
Tuesday, 06 December 2005
Clinical lore suggests that a flare in PBS/IC symptoms occurs in the perimenstrual period, indicating a direct influence of gonadal hormones on pain sensitivity.
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Amitriptyline Shows Good Long-term Results For Painful Bladder/Interstitial Cystitis (PBS/IC) With No Evidence Of Tachyphylaxis
Thursday, 01 December 2005
BERKELEY, CA (UroToday.com) - A prospective, open label study to examine the safety and efficacy of the tricyclic antidepressant amitriptyline concludes that this inexpensive, generic drug shows significant efficacy regarding the amelioration of the hallmark symptoms of the disorder.
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Cystoscopy With Hydrodistension Found To Provide Little Information And Only Short-Lived Improvement In Symptoms
Tuesday, 29 November 2005
BERKELEY, CA (UroToday.com) - Interstitial cystitis (IC) is characterized by chronic urinary urgency, frequency, and/or pelvic pain in the absence on any known etiology.
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Amitriptyline Shows Long-Term Efficacy In The Treatment Of Interstitial Cystitis
Wednesday, 16 November 2005
BERKELEY, CA (UroToday.com) - Interstitial cystitis (IC) is a chronic and debilitating bladder syndrome primarily affecting women that is characterized by suprapubic pain associated with urinary urgency and frequency, and sterile, cytologically sterile urine.
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Risk Factors For Opiate Medication Abuse In Chronic Pain Patients Identified
Monday, 07 November 2005
BERKELEY, CA (UroToday.com) - Painful bladder syndrome / interstitial cystitis can be considered a chronic pain syndrome.
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Functional Magnetic Resonance Demonstrates Areas Of Brain Active When Sensation Of the Desire To Void Is Influenced Intentionally
Tuesday, 01 November 2005
BERKELEY, CA (UroToday.com) - Suprapontine centers are responsible for the voluntary initiation and postponement of micturition.
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Augmented Extracellular ATP Signaling In Painful Bladder Syndrome / Interstitial Cystitis (PBS/IC) Suggests Possibilities Of Novel Therapeutic Approaches
Monday, 31 October 2005
BERKELEY, CA (UroToday.com) - Bladder urothelial cells (BUC) may play a key pathophysiologic role leading to PBS/IC. Epithelial cells lining hollow organs, including the bladder, may have neurosensory-like functions, as the cells can release adenosine triphosphate (ATP) in response to stretch.
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Pathophysiology Of Urgency May Be Distinct From That Of Detrusor Overactivity
Thursday, 27 October 2005
BERKELEY, CA (UroToday.com) - A connexin is a special type of protein composed of an assembly of six subunits that are called connexins.
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Cystoscopy With Hydrodistension Found To Provide Little Information And Only Short-Lived Improvement In Symptoms
Tuesday, 18 October 2005
BERKELEY, CA (UroToday.com) - Interstitial cystitis (IC) is characterized by chronic urinary urgency, frequency, and/or pelvic pain in the absence on any known etiology.
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IC/PBS/BPS 
