The Dual Serotonin and Noradrenaline Reuptake Inhibitor Duloxetine for the Treatment of Interstitial Cystitis: Results of an Observational Study
Monday, 19 February 2007
BERKELEY, CA (UroToday.com) - The pharmacological modulation of the serotonergic system has been reported to achieve amelioration of PBS/IC symptoms.
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SUFU 2007 - Cannabinoid Receptors in Bladder: Novel Therapeutic Targets for Interstitial Cystitis/Painful Bladder Syndrome
Tuesday, 06 February 2007
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Sensitization of Pelvic Nerve Afferents and Mast Cell Infiltration in the Urinary Bladder Following Chronic Colonic Irritation is Mediated by Neuropeptides
Thursday, 04 January 2007
BERKELEY, CA (UroToday.com) - Irritable bowel syndrome and interstitial cystitis frequently overlap.
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American Urological Association Names New Director of Guidelines
Wednesday, 03 January 2007
BALTIMORE, January 2007 — The American Urological Association (AUA) has announced that Heddy Hubbard, Ph.D., M.P.H., R.N., F.A.A.N. will be the new Director of Guidelines for the association. Dr. Hubbard joined the AUA on December 28, 2006.
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Dysuria at Onset of Interstitial Cystitis/Painful Bladder Syndrome in Women
Tuesday, 02 January 2007
BERKELEY, CA (UroToday.com) - Painful urination or "dysuria" has not been considered a prominent part of the PBS/IC syndrome complex, and is more often associated with urinary tract infection or recent urethral instrumentation.
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Emerging Drug Discovery Strategies for Alleviating Neuropathic Pain
Friday, 29 December 2006
BERKELEY, CA (UroToday.com) - It is widely believed that the pain of PBS/IC can ultimately result in central sensitization and become chronic and unrelated to the organ of the primary pathology, the bladder.
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Efficacy of Tricyclic Antidepressant is Associated with Beta2-Adrenoceptor Genotype in Patients with Interstitial Cystitis
Wednesday, 27 December 2006
BERKELEY, CA (UroToday.com) - Tricyclic antidepressant therapy (amitriptyline in particular) is effective in treating the symptoms of PBS/IC. These drugs block the active transport system that is involved in the re-uptake of serotonin and noradrenaline.
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Prevalence and Correlates for Interstitial Cystitis Symptoms in Women Participating in a Health Screening Project
Friday, 24 November 2006
BERKELEY, CA (UroToday.com) - Nine hundred and eighty-one women attending a voluntary health survey project in Vienna underwent a detailed health investigation and completed a questionnaire containing the O'Leary-Sant symptom and problem indexes. Women with symptom scores and problem scores of over 12 were considered most likely to have interstitial cystitis.
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The Molecular Basis of Urgency: Regional Difference of Vanilloid Receptor Expression in the Human Urinary Bladder
Wednesday, 22 November 2006
BERKELEY, CA (UroToday.com) - Transient receptor potential vanilloid-1 receptor (TRPV1) is activated by capsaicin, the drug injected subcutaneously by scientists in an attempt to study C fiber sensitization.
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Report on the NIDDK International Frontiers In PBS/IC Symposium
Monday, 20 November 2006
BETHESDA, MD (UroToday.com) - October 26 - 27, 2006 - The recently concluded NIDDK meeting on Frontiers in Painful Bladder Syndrome / Interstitial Cystitis was extremely successful and well-received. It was chaired by Deborah Erickson, Professor of Urology at the University of Kentucky.
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Safety and Efficacy of Hyperbaric Oxygen Therapy for the Treatment of Interstitial Cystitis: A Randomized, Sham Controlled, Double-Blind Trial.
Wednesday, 11 October 2006
BERKELEY, CA (UroToday.com) - Hyperbaric Oxygen (HBO) therapy aims at ischemia by leading to a net gain in oxygen concentration in tissues.
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Uronate Peaks and Urinary Hyaluronic Acid Levels Correlate With Interstitial Cystitis Severity
Tuesday, 10 October 2006
BERKELEY, CA (UroToday.com) - Several promising markers, led by antiproliferative factor and heparin binding epidermal growth factor-like growth factor may eventually be useful in diagnosing interstitial cystitis.
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EGF and HB-EGF Modulate Inward Potassium Current in Human Bladder Urothelial Cells from Normal and Interstitial Cystitis Patients
Monday, 09 October 2006
BERKELEY, CA (UroToday.com) - There are currently two well-known bladder hypersensory syndromes - overactive bladder (OAB) and interstitial cystitis (BPS/IC). Because BPS/IC is associated with chronic bladder pain, it represents potentially a more challenging clinical problem. There are no treatments that target specifically the bladder sensory pathways.
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Techniques for the Intradetrusor Administration of Botulinum Toxin
Wednesday, 04 October 2006
BERKELEY, CA (UroToday.com) - The rationale for using botulinum toxin (BTX) injections into the bladder in preliminary studies was based on its known effect of blocking the parasympathetic release of acetylcholine, akin to its mechanism of action in skeletal muscle.
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Efficiency of Questionnaires Used to Screen for Interstitial Cystitis
Wednesday, 27 September 2006
BERKELEY, CA (UroToday.com) - Studies have used the OSPI and PUF questionnaires to screen individuals who present with symptoms of BPS/IC and, thereby, determine the prevalence of BPS/IC in a general population.
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