Prevalence and Correlates for Interstitial Cystitis Symptoms in Women Participating in a Health Screening Project
Friday, 24 November 2006
BERKELEY, CA (UroToday.com) - Nine hundred and eighty-one women attending a voluntary health survey project in Vienna underwent a detailed health investigation and completed a questionnaire containing the O'Leary-Sant symptom and problem indexes. Women with symptom scores and problem scores of over 12 were considered most likely to have interstitial cystitis.
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The Molecular Basis of Urgency: Regional Difference of Vanilloid Receptor Expression in the Human Urinary Bladder
Wednesday, 22 November 2006
BERKELEY, CA (UroToday.com) - Transient receptor potential vanilloid-1 receptor (TRPV1) is activated by capsaicin, the drug injected subcutaneously by scientists in an attempt to study C fiber sensitization.
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Report on the NIDDK International Frontiers In PBS/IC Symposium
Monday, 20 November 2006
BETHESDA, MD (UroToday.com) - October 26 - 27, 2006 - The recently concluded NIDDK meeting on Frontiers in Painful Bladder Syndrome / Interstitial Cystitis was extremely successful and well-received. It was chaired by Deborah Erickson, Professor of Urology at the University of Kentucky.
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Safety and Efficacy of Hyperbaric Oxygen Therapy for the Treatment of Interstitial Cystitis: A Randomized, Sham Controlled, Double-Blind Trial.
Wednesday, 11 October 2006
BERKELEY, CA (UroToday.com) - Hyperbaric Oxygen (HBO) therapy aims at ischemia by leading to a net gain in oxygen concentration in tissues.
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Uronate Peaks and Urinary Hyaluronic Acid Levels Correlate With Interstitial Cystitis Severity
Tuesday, 10 October 2006
BERKELEY, CA (UroToday.com) - Several promising markers, led by antiproliferative factor and heparin binding epidermal growth factor-like growth factor may eventually be useful in diagnosing interstitial cystitis.
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EGF and HB-EGF Modulate Inward Potassium Current in Human Bladder Urothelial Cells from Normal and Interstitial Cystitis Patients
Monday, 09 October 2006
BERKELEY, CA (UroToday.com) - There are currently two well-known bladder hypersensory syndromes - overactive bladder (OAB) and interstitial cystitis (BPS/IC). Because BPS/IC is associated with chronic bladder pain, it represents potentially a more challenging clinical problem. There are no treatments that target specifically the bladder sensory pathways.
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Techniques for the Intradetrusor Administration of Botulinum Toxin
Wednesday, 04 October 2006
BERKELEY, CA (UroToday.com) - The rationale for using botulinum toxin (BTX) injections into the bladder in preliminary studies was based on its known effect of blocking the parasympathetic release of acetylcholine, akin to its mechanism of action in skeletal muscle.
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Efficiency of Questionnaires Used to Screen for Interstitial Cystitis
Wednesday, 27 September 2006
BERKELEY, CA (UroToday.com) - Studies have used the OSPI and PUF questionnaires to screen individuals who present with symptoms of BPS/IC and, thereby, determine the prevalence of BPS/IC in a general population.
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Ketamine for Treatment of Catheter Related Bladder Discomfort: A Prospective, Randomized, Placebo Controlled and Double Blind Study
Tuesday, 26 September 2006
BERKELEY, CA (UroToday.com) - Catheter related bladder discomfort is common in patients awakening from anesthesia who have had urinary catheterization during surgery.
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Transient Receptor Potential Vanilloid Receptor Subtype 1 in Painful Bladder Syndrome and its Correlation with Pain
Monday, 25 September 2006
BERKELEY, CA (UroToday.com) - The involvement of C-fiber afferents in urinary frequency and pain associated with BPS/IC and neurogenic detrusor overactivity has been established, but relatively little is known of the ion channels and receptors expressed by these fibers in human urinary disorders.
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Oral Treatment with a Vitamin D3 Analogue (BXL628) has Anti-Inflammatory Effects in Rodent Model of Interstitial Cystitis
Friday, 22 September 2006
BERKELEY, CA (UroToday.com) - The active form of vitamin D, calcitriol or 1,25(OH)2D3, is a secosteroid hormone that has been extensively studied over several years.
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What is the Fate of the Leftover Bladder after Supravesical Diversion for Benign Disease?
Tuesday, 22 August 2006
BERKELEY, CA (UroToday.com) - Ureteroileal cutaneous diversion was propagated by Bricker in 1950 for diversion after cystectomy for bladder cancer.
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Bladder Urothelium in PBS/IC Shows Distinct Differences in Keratin Profiles
Friday, 18 August 2006
BERKELEY, CA (UroToday.com) - Research groups from the Netherlands and Denmark led by Pilar Laguna studied urothelial involvement in PBS/IC by characterizing the keratin phenotype of bladder urothelium in 18 patients with the disorder.
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Poor Response to Antihistamine Therapy in PBS/IC May Relate to Ineffectiveness of Chosen Antihistamine or Weakening of Sphincteric Function
Friday, 11 August 2006
BERKELEY, CA (UroToday.com) - The potent inflammatory mediator histamine and other bioamines (e.g., serotonin) are possibly involved in the pathophysiology of PBS/IC.
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Lack of Efficacy of Pentosan Polysulfate in Some Patients May be Partially Explained by Poor Urinary Excretion
Wednesday, 02 August 2006
BERKELEY, CA (UroToday.com) - Pentosan Polysulfate (PPS) is the only oral medication approved by the United States Food and Drug Administration for interstitial cystitis.
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IC/BPS 
