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IC/PBS/BPS/HBS

UroToday's IC/PBS/BPS section is a repository of the clinical publications, clinical trials and investigative science pertaining to the diagnosis and treatment of interstitial cystitis/painful bladder syndrome/bladder pain syndrome. Also available are conference coverage for all timely IC/PBS/BPS, audio podcasts and downloadable slides from UroToday's slide library.

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Symptom Scales For Painful Bladder Syndrome / Interstitial Cystitis (PBS/IC) Shown To Be Responsive To Change Over Time
Wednesday, 01 March 2006
BERKELEY, CA (UroToday.com) - The O'Leary-Sant Interstitial Cystitis Symptom Index (ICSI) and Problem Index (ICPI) as well at the Wisconsin IC Inventory were evaluated by looking at data derived from a randomized clinical trial conducted by the Interstitial Cystitis Clinical Trials Group.
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Anti-Tumor Necrosis Factor Therapy Suggested As Way To Mitigate The Pathogenesis Of PBS, Neurogenic Cystitis
Thursday, 23 February 2006
BERKELEY, CA (UroToday.com) - PBS/IC is often regarded as a neurogenic cystitis due to symptoms that include pelvic and/or perineal pain, urinary frequency, urgency and nocturia.
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Costs Of PBS/IC Extremely High In An Employed Population
Wednesday, 22 February 2006
BERKELEY, CA (UroToday.com) - Factors that contribute to the cost of PBS/IC include medical and drug utilization related to treatment and diagnosis, loss of work, and attributable conditions like depression and anxiety.
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Detrusor Smooth Muscle Cells May Be Critical In Induction Of Bladder Inflammation Pathophysiology
Tuesday, 21 February 2006
BERKELEY, CA (UroToday.com) - Bladder biopsies from patients with Painful Bladder Syndrome/Interstitial Cystitis (PBS/IC) are characterized by an increased number of activated bladder mast cells in the detrusor.
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Low-Dose Subcutaneous Heparin May Improve Response To Oral Pentosan Polysulfate In Some Patients
Monday, 06 February 2006
BERKELEY, CA (UroToday.com) - Van Ophoven and colleagues studied 3 groups of patients with PBS/IC, all of whom reported efficacy with oral pentosanpolysulfate (PPS).
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Modified Potassium Chloride Test Cannot Differentiate Interstitial Cystitis From Overactive Bladder
Tuesday, 31 January 2006
BERKELEY, CA (UroToday.com) - Philip and colleagues from Cheshire, UK performed a double-blinded study to investigate the effects of potassium chloride on cystometric parameters in 2 clearly defined groups comprising 17 patients' total - established interstitial cystitis (NIDDK criteria) and documented detrusor overactivity (DO).
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Interstitial Cystitis Accounts For 2.8% Of Outpatient Urology Clinic Visits In Canada
Thursday, 26 January 2006
BERKELEY, CA (UroToday.com) - How prevalent in urologic practice are prostatitis, epididymitis, and painful bladder syndrome/interstitial cystitis?
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Could Questionnaires Replace Physiological Testing For Diagnosis?
Tuesday, 24 January 2006
BERKELEY, CA (UroToday.com) - Questionnaires have become widespread in urology and serve as a useful way of gathering detailed information about subjective symptoms, including the effect of a condition or treatment on a patient's quality of life.
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Can A Modified Potassium Sensitivity Test Predict Response To Intravesical Hyaluronic Acid Therapy?
Monday, 09 January 2006
BERKELEY, CA (UroToday.com) - In an English study, 38 patients with interstitial cystitis were administered a modified potassium chloride sensitivity test (PST) and then treated with the intravesical glycosaminoglycan sodium hyaluronate (Cystostat®) weekly for 6 weeks.
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Long-Term Results Of Sacral Neuromodulation For Urgency-Frequency Mandate Caution
Thursday, 05 January 2006
BERKELEY, CA (UroToday.com) - Elhilali and colleagues have reported on the long term results of sacral neuromodulation therapy effectiveness in patients implanted at the McGill University Hospitals over a thirteen year period.
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Antiproliferative Factor (APF) May Contribute To The Leakiness Of The Bladder Epithelial Barrier Seen In PBS/IC
Tuesday, 03 January 2006
BERKELEY, CA (UroToday.com) - Previous reports have suggested that the bladder epithelia barrier may be compromised in PBS/IC.
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Potassium Sensitivity Test Predicts Interstitial Cystitis Treatment Response
Tuesday, 03 January 2006
NEW YORK (Reuters Health) - The potassium sensitivity test can predict the response of interstitial cystitis patients to treatment with glycosaminoglycan-substitution therapy, according to a report in the November BJU International.
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Oral Cyclosporin Proves Effective For PBS/IC In A Randomized, Comparative Study
Thursday, 22 December 2005
BERKELEY, CA (UroToday.com) - Cyclosporin in a daily divided dose of 3mg per kilogram per day was compared with sodium pentosanpolysulfate (Elmiron®) 100mg three times daily in 64 patients with PBS/IC over 6 months of treatment.
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Localization Of The Urge To Void In Patients With Painful Bladder Syndrome (PBS) Differs From Other Groups
Monday, 19 December 2005
BERKELEY, CA (UroToday.com) - The localization of the urge to void seems to involve a wider area in patients with PBS than in those with overactive bladder (OAB), stress incontinence (SI), and asymptomatic controls.
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Hydrodistention Appears To Have Limited Long-Term Benefit For Painful Bladder Syndrome / Interstitial Cystitis (PBS/IC)
Thursday, 15 December 2005
BERKELEY, CA (UroToday.com) - In a large, retrospective study of 185 patients with PBS/IC subjected to hydrodistention under general anesthesia for five minutes and then repeated after emptying for another 5 minutes, 6 month symptomatic improvement was identified in only 5%.
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