Division of Female Pelvic Medicine and Reconstructive Surgery, Chang Gung Memorial Hospital, Linko, Taiwan.

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This study was conducted to determine whether urgency-free interval (UFI) was effective to evaluate the outcome of overactive bladder (OAB) and the correlation of changes between this parameter and urgency episodes.

A randomized placebo-controlled trial was conducted involving 73 women with OAB. The interventions for a 12-week period included a vaginal electric stimulation and oxybutynin (2.5 mg) or placebo three times per day. Identical preintervention and postintervention assessments included the measurement of UFI and warning time (WT). The King's Health Questionnaire, Spearman's correlation coefficient (SCC), Kruskal-Wallis, Mann-Whitney U, and Wilcoxon-signed rank tests were used for analysis.

A positive and significant correlation between the improvements of WT and UFI was noted in the oxybutynin group (p = 0.009). In all groups, none of the SCC revealed significant correlation between the improvement of UFI and urgency episodes (all p >or= 0.145).

The efficacy of UFI in evaluating treatment outcome of OAB was comparable with that of WT in selected modality.

Written by:
Wang AC, Chen MC, Kuo WY, Lin YH, Wang YC, Lo TS.   Are you the author?

Reference:
Int Urogynecol J Pelvic Floor Dysfunct. 2009 Jul;20(7):819-25.
doi:10.1007/s00192-009-0860-7

PubMed Abstract
PMID:19495544

UroToday.com Overactive Bladder (OAB) Section

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