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Overactive Bladder
UroToday's Overactive Bladder section is a repository of the clinical publications, clinical trials and investigative science pertaining to the diagnosis and treatment of overactive bladder. Also available are conference coverage for all timely overactive bladder science, audio podcasts and downloadable slides from UroToday's slide library.
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Kind regards,
Christian Gratzke, MD
Associate Section Editor Overactive Bladder
UroToday International Journal

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SUFU 2008 Winter Meeting - POD #4 - The Validation of a Sham for Posterior Tibial Nerve Stimulation
Wednesday, 30 April 2008
Introduction and Objectives: Posterior tibial nerve stimulation (PTNS) is used to treat urgency and frequency in people with overactive bladder (OAB).
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SUFU 2008 Winter Meeting - POD #6 - The Evolving Role of Office Test Stimulation for Patients Undergoing Sacral Neuromodulation
Wednesday, 30 April 2008
Introduction and Objectives: Sacral neuromodulation (SNS) has become an accepted modality in the treatment of refractory voiding dysfunction.
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SUFU 2008 Winter Meeting - POD #7 - Urodynamic Predictors of Successful Test Stimulation for Sacral Neuromodulation in Patients with Neurologic Disease and Voiding Dysfunction
Wednesday, 30 April 2008
Introduction and Objectives: We evaluated various urodynamic parameters as potential predictors for successful test stimulation for Sacral Neuromodulation in patients with neurologic disease and voiding dysfunction.
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SUFU 2008 Winter Meeting - POD #3 - The Effect of Neuromodulation on Female Sexual Function
Wednesday, 30 April 2008
Introduction and Objectives: Recent studies suggest that Interstim® neuromodulation therapy may improve female sexual dysfunction. We prospectively evaluated women undergoing Interstim® implantation for urgency, frequency, urinary retention or Interstitial Cystitis (IC) to determine if neuromodulation would have any effect on the Female Sexual Function Index (FSFI) or any of its domains (desire, arousal, lubrication, orgasm, satisfaction, pain).
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SUFU 2008 Winter Meeting - POD #8 - Safety and Efficacy of Chronic Pudendal Nerve Stimulation (CPNS): Medium Term Follow Up in Two Centers' Data-Collection
Wednesday, 30 April 2008
Introduction and Objectives: Further clinical evidence for the safety and efficacy of CPNS with tined lead under neurophysiological guidance comes from a two-centre chart-review study. The study aimed at evaluating the efficacy and safety of this therapy in patients with urinary and bowel disorders, such as neurogenic and idiopathic OAB, urinary retention, painfull bladder syndrome (PBS), constipation and sphincter deficit.
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Depressive Symptoms Increase the Incidence of Nocturia: Tampere Aging Male Urologic Study (TAMUS) - Abstract
Monday, 28 April 2008
Department of Urology, Tampere University Hospital, Tampere, Finland.
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Ultrasound Measurement of Bladder Wall Thickness in the Assessment of Voiding Dysfunction - Abstract
Monday, 28 April 2008
Urology Department, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
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√ SUFU 2008 Winter Meeting - Society for Urodynamics and Female Urology Holds International Meeting to Assess Areas of Consensus and Disagreement Regarding Interstitial Cystitis / Bladder Pain Syndrome
Saturday, 26 April 2008
√ Editor's Pick:     BERKELEY, CA (UroToday.com) - Over the last 6 years there have been ongoing efforts around the world to standardize nomenclature, definition, and evaluation of interstitial cystitis/bladder pain syndrome/painful bladder syndrome.
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Predicting Detrusor Overactivity Using a Physician-Based Scoring System - Abstract
Friday, 25 April 2008
King’s College Hospital, London, UK.
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Nocturia in Men Less Than 50 Years of Age May Be Associated with Obstructive Sleep Apnea Syndrome - Abstract
Friday, 25 April 2008
Department of Urology, Gifu University School of Medicine, Gifu, Japan.
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Urinary Nerve Growth Factor Levels Are Increased in Patients with Bladder Outlet Obstruction with Overactive Bladder Symptoms and Reduced After Successful Medical Treatment - Abstract
Monday, 21 April 2008
Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan.
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Overactive Bladder in Children Should Be Strictly Differentiated from Monosymptomatic Nocturnal Enuresis
Thursday, 17 April 2008
BERKELEY, CA (UroToday.com) - A study out of Japan evaluated the prevalence of a concomitant overactive bladder in children with a chief complaint of primary nocturnal enuresis.
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Dual Use of Bladder Anticholinergics and Cholinesterase Inhibitors: Long-Term Functional and Cognitive Outcomes - Abstract
Wednesday, 16 April 2008
Section on Gerontology and Geriatric Medicine, Department of Medicine, School of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA.
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EAU 2008 - Clinical Proof of Concept Study (BLOSSOM) Shows Novel Beta 3 Adrenoceptor Agonist YM178 is Effective and Well Tolerated in the Treatment of Symptoms of Overactive Bladder
Friday, 04 April 2008
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Fesoterodine Dose Response in Subjects With Overactive Bladder Syndrome - Abstract
Wednesday, 02 April 2008
St. Mary's Hospital, Imperial College, London, United Kingdom.
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Promoting World Continence




Focus on Overactive Bladder

Focus on Overactive Bladder condenses a selection of compelling and relevant science - on topic and chosen by the UroToday.com editorial staff.





Podcast - Effective Darifenacin Treatment after Dissatisfaction with Prior Extended-Release Antimuscarinic Therapy






Differential Pharmacological Effects of Antimuscarinic Drugs on Heart Rate: A Randomized, Placebo-Controlled, Double-Blind, Crossover Study with Tolterodine and Darifenacin in Healthy Participants > or = 50 years

- by Brian Olshansky, MD

Darifenacin Treatment for Overactive Bladder in Patients Who Expressed Dissatisfaction With Prior Extended-Release Antimuscarinic Therapy

- by Norman Zinner, MD, et al.

Suburothelial Myofibroblasts in the Human Overactive Bladder and the Effect of Botulinum Neurotoxin Type A Treatment

- by Alexander Roosen, MD and Clare J. Fowler, MD

A Systematic Review and Meta-Analysis of Randomized Controlled Trials with Antimuscarinic Drugs for Overactive Bladder

- by Giacomo Novara, MD, FEBU

Emerging Drugs for Treatment of Overactive Bladder and Detrusor Overactivity

- by Marcus Drake, MD



Two Types of Urgency

- by Philip M. Hanno, MD, MPH - Editor's Pick

Long-Term Efficacy and Safety of Tolterodine in Children with Neurogenic Detrusor Overactivity

- by Pasquale Casale, MD

Defining Overactive Bladder as Hypersensitivity

- by Philip M. Hanno, MD, MPH



Minimally Invasive Therapy for Neurogenic Detrusor Overactivity: A Review

- by Karl-Erik Andersson, Roger Dmochowski and Alan Wein

A Randomized Controlled Study of Posterior Tibial Nerve Stimulation for Overactive Bladder

- by Paula Palma, MD, PhD. et al.

Efficacy and Tolerability of Add-On Trospium Chloride in Patients with Benign Prostate Syndrome and Overactive Bladder: A Noninterventional Trial Showing Use of Flexible Dosing

- by Ulrich Schwantes, PhD, et al.






The second-line management of idiopathic overactive bladder: What is the place of sacral neuromodulation and botulinum toxin-A in contemporary practice?



On the Origins of the Sensory Output from the Bladder: The Concept of Afferent Noise




A Review of Adherence to Drug Therapy in Patients with Overactive Bladder



Sacral Neuromodulation for Treating the Symptoms of Overactive Bladder Syndrome and Non-Obstructive Urinary Retention: More Than 10 Years of Clinical Experience




Urine cytokines suggest an inflammatory response in the overactive bladder: a pilot study

- by Michael Chancellor, MD, et al.

Obesity is associated with a more severe overactive bladder disease state that is effectively treated with once-daily administration of trospium chloride extended release

- by Michael G. Oefelein, MD, et al.

Ten years single surgeon experience with botulinum toxin in the urinary tract; clinical observations and research discovery

- by Michael Chancellor, MD.

The evolution of transdermal therapy for overactive bladder

- by Peter K. Sand, MD

Outcome of a Randomized, Double-Blind, Placebo Controlled Trial of Botulinum A Toxin for Refractory Overactive Bladder

- by Michael K. Flynn, MD, et al.

InterStim Therapy: A Contemporary Approach to Overactive Bladder

- by Neeraj Kohli, MD, MBA and Danielle Patterson, MD

Differential Pharmacological Effects of Antimuscarinic Drugs on Heart Rate: A Randomized, Placebo-Controlled, Double-Blind, Crossover Study with Tolterodine and Darifenacin in Healthy Participants > or = 50 years

- by Brian Olshansky, MD, et al.

Randomized Comparison of Tolterodine With Vaginal Estrogen Cream Versus Tolterodine Alone for the Treatment of Postmenopausal Women With Overactive Bladder Syndrome

- by Ling-Hong Tseng, MD, et al.









The role of industry funding in randomized controlled trials of antimuscarinic medications for overactive bladder

- Session Highlight by Ariana L. Smith, MD from the International Continence Society (ICS) 39th Annual Meeting

State of the Art Lecture: Bladder re-innervation: Can new nerves improve the function of the neurogenic bladder?

- Session Highlight by Ariana L. Smith, MD from the International Continence Society (ICS) 39th Annual Meeting

Is ultrasound bladder wall thickness a better measure than urodynamics for overactive bladder symptoms?

- Session Highlight by Ariana L. Smith, MD from the International Continence Society (ICS) 39th Annual Meeting

Urodynamics/Incontinence/Female Urology: Urodynamic Testing - Identification of Measures of Bladder Sensation in Patients with Overactive Bladder

- Session Highlight by Kathleen Kobashi, MD from the 2009 Annual Meeting of the American Urological Association (AUA)

Session Highlights from the Society for Urodynamics & Female Urology 2009 Winter Meeting

- Exclusive Coverage by UroToday Contributing Medical Editor, William Jaffe, MD

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at The National Institutes of Health (NIH) - UI Symposium

- Session Highlights Reported by Diane K. Newman

Drug Treatment - Lecture Series


- Presented by Karl-Erik Andersson, MD, PhD, and Christopher Chapple, MD, et al. at the Fourth International Consultation on Incontinence (ICI)


Drug Treatment - Committee Meeting Highlights


- Reported by William Jaffe, MD from the Fourth International Consultation on Incontinence (ICI)

Voiding Dysfunction Session Highlights


- From the American Urological Association 2008 Annual Meeting

Urodynamics and Reality


- Presented by Ed McGuire, MD, at the 32nd Winter Urologic Forum

Clinical Proof of Concept Study (BLOSSOM) Shows Novel Beta 3 Adrenoceptor Agonist YM178 is Effective and Well Tolerated in the Treatment of Symptoms of Overactive Bladder

- Presented at the European Association of Urology - 23rd Annual EAU Congress

International Consultation on Incontinence - ICI 2008

- Session Abstracts, Overactive Bladder



 
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