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Overactive Bladder
UroToday's Overactive Bladder section is a repository of the clinical publications, clinical trials and investigative science pertaining to the diagnosis and treatment of overactive bladder. Also available are conference coverage for all timely overactive bladder science, audio podcasts and downloadable slides from UroToday's slide library.
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Kind regards,
Christian Gratzke, MD
Associate Section Editor Overactive Bladder
UroToday International Journal

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Results 511 - 525 of 758
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SUFU 2008 Winter Meeting - POD #20 - The Use of Intra-Detrusor Botulinum Toxin-A in the Elderly
Monday, 05 May 2008
Introduction and Objectives: The intra-detrusor injection of Botulinum toxin-A (BTX-A) is becoming an accepted treatment option for the management of refractory detrusor overactivity (DO).
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SUFU 2008 Winter Meeting - POS #MP24 - Validation of a Real-Time Urodynamic
Monday, 05 May 2008
Introduction and Objectives: To validate a new device, the Urgeometer, for measurement of urinary urgency during urodynamic testing (UDS).
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SUFU 2008 Winter Meeting - POS #BS1 - The Effect of Botulinum Toxin A on Chemical Stimulation of Rat Dorsal Root Ganglion Cells
Friday, 02 May 2008
Introduction and Objectives: Botulinum toxin A (BnTxA) has previously been demonstrated to modulate sensory nerve activity in animal models.
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SUFU 2008 Winter Meeting - POS #BS2 - The Effects of No Donors and Membrane Permeable cGMP Analogue on Murine Bladder Smooth Muscle
Friday, 02 May 2008
Introduction and Objectives: The collection and storage of urine by the detrusor and its periodic expulsion through the bladder neck and urethra are dependent upon complex neural pathways.
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SUFU 2008 Winter Meeting - POS #BS3 - Methionine and Its Derivatives Increase Bladder Excitability by Inhibiting Stretch-Dependent K+ Channels
Friday, 02 May 2008
Introduction and Objectives: During the bladder filling phase, the volume of the urinary bladder increases dramatically, with only minimal increases in intravesical pressure, thereby allowing it to fill more easily.
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SUFU 2008 Winter Meeting - POS #BS4 - Functional and Molecular Identification of pH-Sensitive K+ Channels in Murine Bladder Smooth Muscle
Friday, 02 May 2008
Introduction and Objectives: Bladder contractility is influenced by the resting membrane potential, which is mainly regulated by background K+ conductances.
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SUFU 2008 Winter Meeting - POS #BS6 - Detrusor Overactivity in Spontaneously Hypertensive Rats is Associated with Alternations in Caveolae-Mediated Signaling Events
Friday, 02 May 2008
Introduction and Objectives: Although the cause of detrusor overactivity (DO) is still unclear, aberrant regulation of multiple signaling pathways may be involved in its pathogenesis.
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SUFU 2008 Winter Meeting - POS #BS7 - Urethral Afferent Signaling Leads to Activation of the External Urethral Sphincter and Abdominal Wall Muscles
Friday, 02 May 2008
Introduction and Objectives: Rat voiding includes contraction of the abdominal wall (the VAR) and a pulsatile contraction of the external urethral sphincter (EUS).
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SUFU 2008 Winter Meeting - POS #BS8 - Lower Genitourinary Anatomy and Function of Lysyl Oxidase Like-1 Knockout (LOXL1 KO) Mice With and Without Pelvic Organ Prolapse
Friday, 02 May 2008
Introduction and Objectives: Female pelvic floor dysfunction (FPFD) is a complex and debilitating group of conditions which include urinary incontinence, voiding dysfunction, and pelvic organ prolapse (POP).
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SUFU 2008 Winter Meeting - POS #BS22 - Neuroselective Electrostimulation of the Bladder Afferent Pathways Induces C-fos Expression in the Regions of the Spine Specific for Bladder Afferent C and A-Delta Fibers
Thursday, 01 May 2008
Introduction: C-fos, an immediate early gene which can be activated by increased neuronal activity, allows an accurate quantitative evaluation of nociceptive input reaching the spinal cord.
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SUFU 2008 Winter Meeting - POS #BS20 - Botulinum Toxin Type A Normalizes Alterations in Urothelial ATP and Nitric Oxide Release Induced by Chronic Spinal Cord Injury
Thursday, 01 May 2008
Introduction and Objectives: The purpose of this paper was to simultaneously examine changes in urothelial ATP and nitric oxide (NO) release in normal and spinal cord injured (SCI) animals as well as in spinal cord injured animals treated with botulinum toxin type A (BoNT-A) and to correlate changes in transmitter release with functional changes in bladder contraction frequency and with efferent nerve function.
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SUFU 2008 Winter Meeting - POS #BS18 - A One-Week Sub-Acute Safety Evaluation of a Novel Transcutaneous Stimulator in a Canine Model
Thursday, 01 May 2008
Introduction and Objectives: The use of electrical stimulation for the treatment of Overactive Bladder and other lower urinary tract dysfunctions has gained increased interest in recent years.
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Urinary Nerve Growth Factor Level Could be a Potential Biomarker for Diagnosis of Overactive Bladder - Abstract
Wednesday, 30 April 2008
Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan.
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SUFU 2008 Winter Meeting - POD #1 - Changes in Urinary Urgency, Frequency, and Pelvic Pain After Sacral Neuromodulation and the Role of the Global Response Assessment
Wednesday, 30 April 2008
Introduction and Objectives: In chronic urologic conditions, evaluating patients’ perceptions of symptom improvement in addition to assessing objective parameters is crucial when evaluating treatments.
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SUFU 2008 Winter Meeting - POD #2 - Unilateral Versus Bilateral Stage I Neuromodulation for the Treatment of Refractory Voiding Dysfunction
Wednesday, 30 April 2008
Introduction and Objectives: Sacral neuromodulation has become an established therapy for the treatment of refractory voiding dysfunction.
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Promoting World Continence




Focus on Overactive Bladder

Focus on Overactive Bladder condenses a selection of compelling and relevant science - on topic and chosen by the UroToday.com editorial staff.





Podcast - Effective Darifenacin Treatment after Dissatisfaction with Prior Extended-Release Antimuscarinic Therapy






Differential Pharmacological Effects of Antimuscarinic Drugs on Heart Rate: A Randomized, Placebo-Controlled, Double-Blind, Crossover Study with Tolterodine and Darifenacin in Healthy Participants > or = 50 years

- by Brian Olshansky, MD

Darifenacin Treatment for Overactive Bladder in Patients Who Expressed Dissatisfaction With Prior Extended-Release Antimuscarinic Therapy

- by Norman Zinner, MD, et al.

Suburothelial Myofibroblasts in the Human Overactive Bladder and the Effect of Botulinum Neurotoxin Type A Treatment

- by Alexander Roosen, MD and Clare J. Fowler, MD

A Systematic Review and Meta-Analysis of Randomized Controlled Trials with Antimuscarinic Drugs for Overactive Bladder

- by Giacomo Novara, MD, FEBU

Emerging Drugs for Treatment of Overactive Bladder and Detrusor Overactivity

- by Marcus Drake, MD



Two Types of Urgency

- by Philip M. Hanno, MD, MPH - Editor's Pick

Long-Term Efficacy and Safety of Tolterodine in Children with Neurogenic Detrusor Overactivity

- by Pasquale Casale, MD

Defining Overactive Bladder as Hypersensitivity

- by Philip M. Hanno, MD, MPH



Minimally Invasive Therapy for Neurogenic Detrusor Overactivity: A Review

- by Karl-Erik Andersson, Roger Dmochowski and Alan Wein

A Randomized Controlled Study of Posterior Tibial Nerve Stimulation for Overactive Bladder

- by Paula Palma, MD, PhD. et al.

Efficacy and Tolerability of Add-On Trospium Chloride in Patients with Benign Prostate Syndrome and Overactive Bladder: A Noninterventional Trial Showing Use of Flexible Dosing

- by Ulrich Schwantes, PhD, et al.






The second-line management of idiopathic overactive bladder: What is the place of sacral neuromodulation and botulinum toxin-A in contemporary practice?



On the Origins of the Sensory Output from the Bladder: The Concept of Afferent Noise




A Review of Adherence to Drug Therapy in Patients with Overactive Bladder



Sacral Neuromodulation for Treating the Symptoms of Overactive Bladder Syndrome and Non-Obstructive Urinary Retention: More Than 10 Years of Clinical Experience




Urine cytokines suggest an inflammatory response in the overactive bladder: a pilot study

- by Michael Chancellor, MD, et al.

Obesity is associated with a more severe overactive bladder disease state that is effectively treated with once-daily administration of trospium chloride extended release

- by Michael G. Oefelein, MD, et al.

Ten years single surgeon experience with botulinum toxin in the urinary tract; clinical observations and research discovery

- by Michael Chancellor, MD.

The evolution of transdermal therapy for overactive bladder

- by Peter K. Sand, MD

Outcome of a Randomized, Double-Blind, Placebo Controlled Trial of Botulinum A Toxin for Refractory Overactive Bladder

- by Michael K. Flynn, MD, et al.

InterStim Therapy: A Contemporary Approach to Overactive Bladder

- by Neeraj Kohli, MD, MBA and Danielle Patterson, MD

Differential Pharmacological Effects of Antimuscarinic Drugs on Heart Rate: A Randomized, Placebo-Controlled, Double-Blind, Crossover Study with Tolterodine and Darifenacin in Healthy Participants > or = 50 years

- by Brian Olshansky, MD, et al.

Randomized Comparison of Tolterodine With Vaginal Estrogen Cream Versus Tolterodine Alone for the Treatment of Postmenopausal Women With Overactive Bladder Syndrome

- by Ling-Hong Tseng, MD, et al.









The role of industry funding in randomized controlled trials of antimuscarinic medications for overactive bladder

- Session Highlight by Ariana L. Smith, MD from the International Continence Society (ICS) 39th Annual Meeting

State of the Art Lecture: Bladder re-innervation: Can new nerves improve the function of the neurogenic bladder?

- Session Highlight by Ariana L. Smith, MD from the International Continence Society (ICS) 39th Annual Meeting

Is ultrasound bladder wall thickness a better measure than urodynamics for overactive bladder symptoms?

- Session Highlight by Ariana L. Smith, MD from the International Continence Society (ICS) 39th Annual Meeting

Urodynamics/Incontinence/Female Urology: Urodynamic Testing - Identification of Measures of Bladder Sensation in Patients with Overactive Bladder

- Session Highlight by Kathleen Kobashi, MD from the 2009 Annual Meeting of the American Urological Association (AUA)

Session Highlights from the Society for Urodynamics & Female Urology 2009 Winter Meeting

- Exclusive Coverage by UroToday Contributing Medical Editor, William Jaffe, MD

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at The National Institutes of Health (NIH) - UI Symposium

- Session Highlights Reported by Diane K. Newman

Drug Treatment - Lecture Series


- Presented by Karl-Erik Andersson, MD, PhD, and Christopher Chapple, MD, et al. at the Fourth International Consultation on Incontinence (ICI)


Drug Treatment - Committee Meeting Highlights


- Reported by William Jaffe, MD from the Fourth International Consultation on Incontinence (ICI)

Voiding Dysfunction Session Highlights


- From the American Urological Association 2008 Annual Meeting

Urodynamics and Reality


- Presented by Ed McGuire, MD, at the 32nd Winter Urologic Forum

Clinical Proof of Concept Study (BLOSSOM) Shows Novel Beta 3 Adrenoceptor Agonist YM178 is Effective and Well Tolerated in the Treatment of Symptoms of Overactive Bladder

- Presented at the European Association of Urology - 23rd Annual EAU Congress

International Consultation on Incontinence - ICI 2008

- Session Abstracts, Overactive Bladder



 
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Results 511 - 525 of 758

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