Divisions of Urology, Departments of Surgery, McGill University, Montreal, Quebec, and University of Toronto, Toronto, Ontario, Canada.

To evaluate the pregnancy outcomes of two groups of oligospermic men with varicocele, one having a varicocelectomy (group 1) and the other electing not to have surgery (group 2), as varicocele represents the most common factor associated with male infertility and most reports indicate that varicocelectomy has a beneficial effect on male fertility and pregnancy outcome.

We retrospectively reviewed consecutive oligospermic men who had microsurgical varicocelectomy (233, group 1) between September 1996 and January 2002 and a consecutive group of oligospermic men with varicoceles who elected not to have surgery (127, group 2). The outcome measures included changes in semen variables, partner pregnancy rates (assisted and unassisted) and use of assisted reproductive technologies (ART).

The mean sperm concentration and motility increased significantly after varicocelectomy (P < 0.05). The natural pregnancy rate in group 1 (38%) was higher than in group 2 (30%). The use of ART was significantly greater in group 2 than group 1. In the subset of couples with bilateral varicocele, the natural pregnancy rate was significantly higher in group 1 than group 2 (48% vs 15%, respectively, P = 0.008).

This study suggests that the natural pregnancy rate is higher after varicocelectomy than in those not having surgery, although the difference was not statistically significant. However, in the subset of couples with bilateral varicocele, the spontaneous pregnancy rates were significantly higher after surgery.

Written by:
Baazeem A, Boman JM, Libman J, Jarvi K, Zini A.   Are you the author?

Reference:
BJU Int. 2009 Mar 26. Epub ahead of print.
doi: 10.1111/j.1464-410X.2009.08431.x

PubMed Abstract
PMID:19338535

UroToday.com Male Infertility and Reproduction Section

Please log-in or register in order to submit comments.

Powered by AkoComment!