√ Beyond the Abstract - A 64-year-old man with low-risk prostate cancer: Review of prostate cancer treatment, by Sandip M. Prasad, MD and Martin G. Sanda, MD
Tuesday, 18 August 2009
√ Editor's Pick: BERKELEY, CA (UroToday.com) -
Can increased utilization of active surveillance rescue the survival benefits of PSA screening?
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√ Editorial - Two Types of Urgency
Thursday, 21 May 2009
√ Editor's Pick: BERKELEY, CA (UroToday.com) -
Urgency Is Not Just Urgency
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√ Editorial - Patient Anxiety About Prostate Cancer Independently Predicts Early Initiation of Androgen Deprivation Therapy for Biochemical Cancer Recurrence in Older Men: A Prospective Cohort Study
Wednesday, 25 March 2009
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Dr. William Dale and associates reported on the influence of anxiety when a patient with prostate cancer (CaP) and biochemical recurrence (BCR) initiates androgen deprivation therapy (ADT).
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√ Beyond the Abstract - A 1-Year, Open Label, Randomized Phase II Dose Finding Study of Degarelix for the Treatment of Prostate Cancer in North America
Monday, 02 March 2009
√ BERKELEY, CA (UroToday.com) - Degarelix is a new gonadotropin-releasing hormone (GnRH) receptor blocker that binds to pituitary GnRH receptors, immediately blocking gonadotropin release, which results in rapid suppression of testosterone production1.
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√ Beyond the Abstract - Impact of Prostate Median Lobe Anatomy on Robotic-Assisted Laparoscopic Prostatectomy
Tuesday, 06 January 2009
√ Editor's Pick: BERKELEY, CA (UroToday.com) - The idea to investigate the challenges associated with operating on men with a significant median lobe came when we were performing a RALP on a patient with an extremely large median lobe.
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√ Editorial - Exploring Causes for Declining Prostate Cancer Mortality Rates in the United States
Monday, 05 January 2009
√ Editor's Pick: BERKELEY, CA (UroToday.com) - A question that has never been clearly answered is, following the introduction of PSA screening in the US in 1989, why prostate cancer (CaP) deaths increased between 1989 and 1993, then decreased from 1993 to 2003.
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√ Editorial - The Influence of Statin Medications on Prostate-specific Antigen Levels
Monday, 10 November 2008
√ Editor's Pick: BERKELEY, CA (UroToday.com) - According to a report by Dr. Robert J. Hamilton and associates that appears in the November 5, 2008 issue of the Journal of the National Cancer Institute, statin use lowers PSA levels, and as a result may confound the detection of prostate cancer (CaP) in these patients.
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√ Editorial - Association of Gadolinium Based Magnetic Resonance Imaging Contrast Agents and Nephrogenic Systemic Fibrosis
Wednesday, 15 October 2008
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Every physician who orders MRI scans for his or her patients should read this article.
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√ Editorial - A Randomized Controlled Trial of Nephrostomy Placement Versus Tubeless Percutaneous Nephrolithotomy
Tuesday, 23 September 2008
√ Editor's Pick: BERKELEY, CA (UroToday.com) - In 1985, I visited with the venerable Mr. John Wickham at the Institute of Urology in London.
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√ Beyond the Abstract - Serum Calcium and Incident and Fatal Prostate Cancer in the National Health and Nutrition Examination Survey
Wednesday, 17 September 2008
√ Editor's Pick: BERKELEY, CA (UroToday.com) - In our recent report, we show that men in the upper tertile of the normal distribution of serum calcium have an approximately 3-fold increased risk of fatal prostate cancer later in life.
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√ Editorial - Parental Subfecundity and Risk of Decreased Semen Quality in the Male Offspring: A Follow-up Study
Wednesday, 17 September 2008
√ Editor's Pick: BERKELEY, CA (UroToday.com) - This study assessed the impact of parental subfertility, which did not require intervention, on the semen parameters of the male offspring utilizing a population-based, Danish follow-up study conducted in 2005-2006.
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√ Editorial -- Hemorrhage Following Percutaneous Renal Surgery: Characterization of Angiographic Findings
Tuesday, 09 September 2008
√ Editor's Pick: BERKELEY, CA (UroToday.com) - In this award winning manuscript, the authors review the incidence, cause, and diagnosis of vascular complications in more than a score of experience with percutaneous renal surgery in 4,695 patients.
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√ Serum Calcium and Incident and Fatal Prostate Cancer in the National Health and Nutrition Examination Survey - Abstract
Tuesday, 09 September 2008
Comprehensive Cancer Center of Wake Forest University, Medical Center Boulevard, Winston-Salem, NC 27157.
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√ Editorial - HIV and Prostate Cancer: A Systematic Review of the Literature
Thursday, 04 September 2008
√ Editor's Pick: BERKELEY, CA (UroToday.com) - In the online edition of Prostate Cancer and Prostatic Diseases, Dr. Jonathan Silberstein and his colleagues presented a systematic review of HIV and prostate cancer (CaP).
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√ Editorial - Mayo Clinic Validation of the D'Amico Risk Group Classification for Predicting Survival Following Radical Prostatectomy
Thursday, 15 May 2008
√ Editor's Pick:
BERKELEY, CA (UroToday.com) - Dr. Boorjian and colleagues from the Mayo Clinic validated the D’Amico risk classification of predicting survival following radical prostatectomy (RP) using their single institution cohort of 7,591 patients.
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√ Editorial - Comparison of Blade Temperature Dynamics after Activation of Harmonic Ace Scalpel and the Ultracision Harmonic Scalpel LCS-K5
Thursday, 01 May 2008
√ Editor's Pick:
BERKELEY, CA (UroToday.com) - Not all harmonic shears are created equal - surgeon beware.
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√ SUFU 2008 Winter Meeting - Society for Urodynamics and Female Urology Holds International Meeting to Assess Areas of Consensus and Disagreement Regarding Interstitial Cystitis / Bladder Pain Syndrome
Saturday, 26 April 2008
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Over the last 6 years there have been ongoing efforts around the world to standardize nomenclature, definition, and evaluation of interstitial cystitis/bladder pain syndrome/painful bladder syndrome.
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√ Editorial - Association of Preterm Birth with Long-Term Survival, Reproduction, and Next-Generation Preterm Birth
Friday, 25 April 2008
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Preterm birth (birth < 37 weeks) is a major cause of infant morbidity and mortality.
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√ Editorial - Trends in Gleason Score: Concordance Between Biopsy and Prostatectomy over 15 Years
Thursday, 27 March 2008
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Gleason score remains one of the strongest prognostic predictors of treatment outcome in patients with prostate cancer (CaP).
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√ Editorial - Single-Port Laparoscopic Surgery in Urology: Initial Experience
Thursday, 13 March 2008
√ Editor's Pick: BERKELEY, CA (UroToday.com) - The hottest area of minimally invasive surgery is now that of NOTES (natural orifice transluminal endoscopic surgery) and SPA (single port access).
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√ Editorial - Cumulative Association of Five Genetic Variants with Prostate Cancer
Thursday, 21 February 2008
√ Editor's Pick: BERKELEY, CA (UroToday.com) - In addition to age, race, and a positive family history it is now known that variants in chromosomal regions are associated with a risk of prostate cancer (CaP).
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√ Editorial - Absence of Cancer Diagnosis and Treatment in Elderly Medicaid-Insured Nursing Home Residents
Thursday, 14 February 2008
√ Editor's Pick: BERKELEY, CA (UroToday.com) - A study in the January 2008 issue of the Journal of the National Cancer Institute suggests that Medicaid patients in nursing home care receive limited cancer services.
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√ Renal Function Outcomes in Patients Treated with Renal Masses Smaller than 4 cm by Ablative and Extirpative Techniques
Thursday, 14 February 2008
√ Editor's Pick:
BERKELEY, CA (UroToday.com) - This is an extremely important report of the importance of preserving as much normal functioning renal tissue as possible when treating patients with renal tumor disease.
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√ Docetaxel Plus Prednisone or Mitoxantrone Plus Prednisone for Advanced Prostate Cancer: Updated Survival in the TAX 327 Study
Thursday, 17 January 2008
√ Editor's Pick:
BERKELEY, CA (UroToday.com) - The TAX 327 study was reported in 2004 and evaluated patients with hormone-refractory prostate cancer (HRPC) in three treatment arms; docetaxel 75mg/m2 every 3 weeks (D3P), docetaxel 30mg/ m2 weekly (D1P), or mitoxantrone 12 m2 every 3 weeks (MP), each with prednisone 5mg twice daily.
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√ A Phase II Clinical Trial of Sorafenib in Androgen-Independent Prostate Cancer
Thursday, 17 January 2008
√ Editor's Pick:
BERKELEY, CA (UroToday.com) - In the January 1, 2008 issue of Clinical Cancer Research, Dr. Dahut and colleagues report a Phase II trial of Sorafenib in androgen-independent prostate cancer (AICaP).
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√ Obesity-Related Plasma Hemodilution and PSA Concentration among Men with Prostate Cancer
Thursday, 10 January 2008
√ Editor's Pick:
BERKELEY, CA (UroToday.com) -The important association that increased circulating plasma volumes in obese men may hemodilute PSA and result in lower levels is reported in the November 21, 2007 issue of the Journal of the American Medical Association by Dr. Banez and associates.
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√ Obesity and Mortality in Men with Locally Advanced Prostate Cancer
Thursday, 10 January 2008
√ Editor's Pick:
BERKELEY, CA (UroToday.com) - An analysis of RTOG 85-31 patients suggests that increased body mass index (BMI) is associated with increased prostate cancer specific mortality (PCSM). The report appears in the online version of Cancer and is authored by Dr. Efstathiou and collaborators.
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√ Androgen Deprivation Therapy for Localized Prostate Cancer and the Risk of Cardiovascular Mortality
Thursday, 10 January 2008
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Androgen deprivation therapy (ADT) is associated with metabolic syndrome, which includes the development of type II diabetes mellitus and coronary artery disease.
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√ The Phoenix Definition of Biochemical Failure Predicts for Overall Survival in Patients with Prostate Cancer
Thursday, 03 January 2008
√ Editor's Pick: BERKELEY, CA (UroToday.com) - The Phoenix definition of prostate cancer biochemical failure (BF) following radiotherapy (XRT) is a more robust determinant of patient outcome compared with the ASTRO definition according to a report in the online version of Cancer, by Dr. Abramowitz and colleagues.
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√ Percutaneous Core Biopsy for Renal Masses: Indications, Accuracy and Results
Friday, 09 November 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Heads-up – paradigm shift on the horizon!
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√ Laparoscopic Radical Cystectomy for Cancer: Oncological Outcomes at up to 5 years
Friday, 28 September 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - This article published in the British
Journal of Urology International by Georges-Pascal and Gill detail the
oncologic findings and short-term recovery from laparoscopic radical
cystectomy for clinically organ confined bladder cancer. The authors
evaluated 37 patients who underwent laparoscopic radical cystectomy
from 1999 to 2005.
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√ Gonadal Function in Males after Chemotherapy for Early-Stage Hodgkin's Lymphoma Treated in Four Subsequent Trials - European Organization for Research and Treatment of Cancer: EORTC Lymphoma Group and the Groupe d'Étude des Lymphomes de l'Adulte
Wednesday, 25 July 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Few studies have evaluated the impact of contemporary chemotherapy on fertility in young men treated for early stage lymphoma.
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√ EPCA-2: A Highly Specific Serum Marker for Prostate Cancer
Monday, 16 July 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - The steady decrease in prostate cancer mortality is indirect evidence that prostate cancer early detection using serum PSA and the digital rectal examination saves lives.
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√ Under Diagnosis and Over Diagnosis of Prostate Cancer: Under Diagnosis and Over Diagnosis of Prostate Cancer in a Screening Population with Serum PSA 2 to 10 ng/ml
Tuesday, 03 July 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - According to reports from the US and Europe it is more common that prostate cancer (CaP) is under diagnosed than over diagnosed. Both studies appear in the July 2007 issue of the Journal of Urology.
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√ The Current State of Miniature in Vivo Laparoscopic Robotics
Thursday, 28 June 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Firstly, I would like to say kudos to Vip Patel on the publication of Volume 1, number 1 of the new Journal of Robotic Surgery.
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√ Influence of Androgen Suppression Therapy for Prostate Cancer on the Frequency and Timing of Fatal Myocardial Infarctions
Monday, 25 June 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Recent studies have suggested that patients treated with androgen deprivation therapy for more than 12 months may exhibit nearly a 50% risk of developing the metabolic syndrome.
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√ Temsirolimus, Interferon Alfa, or Both for Advanced Renal-Cell Carcinoma
Tuesday, 19 June 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Temsirolimus is a specific inhibitor of mTOR kinase a key component of intracellular signaling involved in cell proliferation.
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√ Remote Telepresence Surgery: The Canadian Experience
Thursday, 07 June 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - This important report from Canada presents 22 telerobotic general surgery laparoscopy cases performed by two surgeons over a distance of 400 kilometers; from a teaching hospital in Hamilton, Ontario to a community hospital in rural Northern Ontario.
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√ Burch Colposuspension versus Fascial Sling to Reduce Urinary Stress Incontinence
Wednesday, 30 May 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Significant variability exists in the selection of anti-incontinence procedures by both urologists and gynecologists. While pubovaginal sling procedures have gained significant popularity in the last 10 years, few randomized trials have compared their efficacy and safety to traditional retropubic procedures.
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√ Matrix Metalloproteinase Polymorphisms Are Associated with Bladder Cancer Invasiveness
Wednesday, 09 May 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - While early cystectomy is indicated in select patients with polychronotropic stage Ta, T1, and CIS bladder cancer, the standard of care to prevent tumor progression for these patients continues to be intravesical BCG.
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√ Age at Surgery for Undescended Testis and Risk of Testicular Cancer
Tuesday, 08 May 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - While all urologists would agree that an undescended testis found in a school-age boy should be treated with an inguinal orchidopexy, whether the procedure results in a decrease in testicular cancer risk remains unclear.
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√ Complications of 2,775 Urological Laparoscopic Procedures: 1993 to 2005
Monday, 26 March 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - In this very large, long-term, retrospective study in which nearly 85% of the laparoscopic procedures were nonpelvic (e.g. renal, adrenal, or retroperitoneal), the overall complication rate was 22%: 4.7% (intraoperative) and 17.5% (postoperative); the mortality rate was 0.07%.
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√ Post-Percutaneous Nephrolithotomy Extensive Hemorrhage: A Study of Risk Factors
Wednesday, 21 March 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - This is by far the most comprehensive review of bleeding complications after percutaneous nephrolithotomy published to date.
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√ Effect of Advanced Age on Laparoscopic Urologic Procedures
Wednesday, 21 March 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Quite simply, in any laparoscopic procedure there are two factors, the surgeon and the patient.
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√ Laparoscopic Versus Open Radical Nephrectomy for Xanthogranulomatous Pyelonephritis: Contemporary Outcomes Analysis
Wednesday, 14 March 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - It was not until 9 years after the initial laparoscopic nephrectomy, that the first report on using this technique for xanthogranulomatous pyelonephritis (XGP) emerged from Washington University.
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√ Time to an Undetectable Prostate-Specific Antigen (PSA) after Androgen Suppression Therapy for Postoperative or Postradiation PSA Recurrence and Prostate Cancer-Specific Mortality (p NA)
Tuesday, 13 March 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Prostate cancer is the most common malignancy in men.
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√ Weekly Docetaxel and Prednisolone versus Prednisolone Alone in Androgen-Independent Prostate Cancer: A Randomized Phase II Study
Friday, 02 March 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - In 2004 two large randomized clinical trials demonstrated that docetaxel based chemotherapy improved survival in androgen-independent prostate cancer (AICAP).
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√ Inhibitory Effect of Snake Venom Toxin from Vipera lebetina turanica on Hormone-Refractory Human Prostate Cancer Cell Growth: Induction of Apoptosis Through Inactivation of Nuclear Factor ΚB
Thursday, 01 March 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Snake venom as therapeutic treatment of cancer?
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√ Double-Blinded Randomized Study of High-Dose Calcitriol Plus Docetaxel Compared With Placebo Plus Docetaxel in Androgen-Independent Prostate Cancer: A Report From the ASCENT Investigators
Wednesday, 28 February 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Calcitriol is the natural ligand for the Vitamin D receptor and is known to inhibit prostate cancer (CaP) proliferation, invasiveness, and angiogenesis and to induce apoptosis.
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√ Relevance of the Prostate-Specific Antigen (PSA) Nanotest Compared to the Classical PSA Test in the Organized Mass Screening of Prostate Cancer
Friday, 23 February 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - A simple finger prick of blood collected on blotting paper and mailed into a lab had accurate correlation with the standard PSA assay in men with PSA levels less than 5ng/ml, according to an online report in the BJU International by Dr. Azzouzi and associates in France.
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