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Exclusion of Inflammation in the Differential Diagnosis of an Elevated Prostate-Specific Antigen (PSA) - Abstract Show Comments PDF Print E-mail
  
Friday, 30 January 2009

James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.

Prostate inflammation can lead to an elevation in the serum PSA concentration and confound the use of PSA kinetics. This can have considerable clinical consequences, since these measurements form the basis for important clinical decisions. Thus, there has been investigation into ways to decrease the confounding from inflammation, including repeat PSA measurements after a period of observation or a course of empiric antibiotics. This article reviews the evidence about elevations in PSA due to prostatitis and describes the controversy over the optimal approach to reduce its confounding impact on prostate cancer screening.

Written by:
Loeb S, Gashti SN, Catalona WJ.   Are you the author?

Reference:
Urol Oncol. 2009 Jan-Feb;27(1):64-6.
doi:10.1016/j.urolonc.2008.04.002

PubMed Abstract
PMID:19111800

UroToday.com Prostatitis Section

 

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