√ The Prognostic Role of a Gene Signature from Tumorigenic Breast-Cancer Cells
Thursday, 22 February 2007
√ Editor's Pick: √ BERKELEY, CA (UroToday.com) - A gene expression profile in human breast tumors correlates with metastasis-free survival and overall survival for several tumor types to include prostate cancer (CaP), according to a report in the January 18, 2007 edition of the New England Journal of Medicine.
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√ Brief Report: Prepubertal Gynecomastia Linked to Lavender and Tea Tree Oils
Friday, 16 February 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Prepubertal gynecomastia is uncommon and idiopathic in over 90% of cases.
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√ Variation in the Definition of Biochemical Recurrence in Patients Treated for Localized Prostate Cancer: The AUA Prostate Guidelines for Localized CaP Update Panel Report & Recommendations for a Standard in the Reporting of Surgical Outcomes
Thursday, 15 February 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - One of the problems with prostate cancer outcomes studies is the lack of standardization in the definition of "treatment failure".
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√ Sorafenib in Advanced Clear-Cell Renal-Cell Carcinoma
Thursday, 08 February 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - In the January issue of The New England Journal of Medicine, Escudier and colleagues for the TARGET Study Group report the results of a Phase III trial designed to evaluate the efficacy of sorafenib in metastatic renal cancer.
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√ Sunitinib versus Interferon Alfa in Metastatic Renal-Cell Carcinoma
Thursday, 08 February 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - In this multicenter trial published in the January 11th issue of The New England Journal of Medicine,
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√ Survival Associated with Treatment vs. Observation of Localized Prostate Cancer in Elderly Men
Wednesday, 31 January 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Without randomized trials of treatment vs. observation in elderly men with prostate cancer (CaP), it has been the assumption that these men will succumb to other causes.
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√ Short-Term Impact of a Laparoscopic “Mini-Residency” Experience on Postgraduate Urologists’ Practice Patterns
Thursday, 18 January 2007
√ Editor's Pick: BERKELEY, CA (UroToday.com) - "A difference to be a difference must make a difference" was attributed to Gertrude Stein. The goal of all teaching and training is to develop this "higher" level of knowledge or skill, but not all efforts to instruct result in an effective difference.
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√ Adjuvant Radiotherapy for Pathologically Advanced Prostate Cancer: A Randomized Clinical Trial
Tuesday, 19 December 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Despite the number of radical prostatectomies performed around the world, the role of adjuvant radiotherapy in the management of patients with locally advanced prostate cancer remains controversial.
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√ Phase II Trial of Interferon in Combination with Thalidomide for Metastatic Renal Cell Carcinoma
Monday, 20 November 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Both thalidomide and -interferon (IFN) have been utilized as monotherapy in the treatment of patients with metastatic renal cell carcinoma (RCC), each with modest evidence of activity and acceptable toxicity profiles.
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√ Obesity, Diabetes, and Risk of Prostate Cancer: Results from the Prostate Cancer Prevention Trial
Wednesday, 15 November 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - The association between obesity and prostate cancer risk remains controversial.
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√ PSA Velocity Greater Than 2 NG/ML the Year Before Diagnosis Independently Predicts Prostate Cancer Mortality in Men Treated with Radical Prostatectomy or Radiotherapy
Tuesday, 14 November 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - In the past, prostate cancer risk stratification before definitive treatment had been largely based on preoperative serum PSA, Gleason score, clinical stage, and the percent of positive biopsies on biopsy. Recently, PSA velocity before diagnosis has been increasingly implicated in prostate cancer prognosis.
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√ Fatty Fish Consumption Associated with Decreased Risk of Renal Cancer in Women
Wednesday, 18 October 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - The consumption of fatty fish such as salmon, herring, and mackerel has been associated with a reduction in the incidence of prostate cancer. This has not been previously studied in other urological malignancies.
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√ Model Predicts Survival Time in Patients with Recurrent Renal Cell Carcinoma
Tuesday, 03 October 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - In the July 1, 2006 issue of the Journal of Clinical Oncology, Dr. Eggener and associates at Memorial Sloan Kettering Cancer Center describe a model that stratifies patients with a recurrence of renal cell carcinoma (RCCA) by risk factors to predict survival time.
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√ The Effects of the Dual 5 Alpha -Reductase Inhibitor Dutasteride on Localized Prostate Cancer - Results From a 4-Month Pre-Radical Prostatectomy Study
Monday, 02 October 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Finasteride, a 5- reductase inhibitor reduced the prevalence of prostate cancer (CaP) in the Prostate Cancer Prevention Trial.
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√ Nomogram to Predict The Risk Of Renal Insufficiency Following Radical Or Partial Nephrectomy
Wednesday, 13 September 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - For many years, radical nephrectomy remained the gold standard for oncologic control of renal neoplasms.
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√ 24th WCE 2006 - VP2-06 & VP2-22 Minimally Invasive NSS
Thursday, 24 August 2006
√ Editor's Pick: Discussed August 17th, 2006 - VP2-06.Five-year outcomes of laparoscopic partial nephrectomy. B. B. Lane and I.S. Gill, Cleveland Clinic, Cleveland, OH, U.S.A.
VP 2-22. Laparoscopic renal cryoablation: oncological outcomes at 5 years. N. Hegarity, J. H. Kaouk, E. M. Remer, C. M. O’Malley, B. I. Chun, M. Aron, J. R. Colombo, G. P. Haber, O. Ukimura, M. Spaliviero, M. M. Desai, A. C. Novick, and I. S. Gill. Cleveland Clinic, Cleveland, OH, U.S.A.
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√ When a Patient is Diagnosed with Prostate Cancer, what Determines Whether he will Receive Early Androgen Ablation? Study Shows that his Choice of Urologist may be More Important Than Tumor Characteristics
Wednesday, 16 August 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - While the benefits of androgen ablation therapy have been well documented in patients with locally advanced and metastatic prostate cancer, there is a paucity of evidence its role in patients with low-grade, low-stage disease.
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√ Sunitinib in Patients with Metastatic Renal Cell Carcinoma
Monday, 24 July 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - The treatment of advanced renal cell carcinoma [RCC] is undergoing a paradigm shift with the recent introduction of anti-angiogenic therapy that either directly inhibits vascular endothelial growth factor or disrupts signal transduction favorable to vascular development through multi-kinase inhibitors.
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√ Sorafenib In Renal Cell Carcinoma: Results Of the Phase II Placebo-Controlled Randomized Discontinuation Trial
Wednesday, 19 July 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Sorafenib was recently approved by the FDA as a systemic therapy option for metastatic renal cell carcinoma (RCC) in part due to the data from this phase II placebo-controlled randomized discontinuation trial.
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√ Botulinum-A Toxin Detrusor Injections Appear To Be Effective And Safe In Treating Nonneurogenic Detrusor Overactivity In Children
Friday, 14 July 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - The use of botulinum-A toxin (BTX) in treating the lower urinary tract continues to grow.
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√ Increased Serum Levels Of Bone-specific Alkaline Phosphatase Correlate With Shorter Survival In Men With Hormone Refractory Prostate Cancer
Wednesday, 05 July 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Metastatic prostate cancer (CaP) is primarily characterized by osteoblastic bone lesions, although both osteoclasts and osteoblasts demonstrate increased activity. Specific markers associating bone progression with survival in CaP was reported by Dr. Cook and colleagues in the June 1, 2006 issue of Clinical Cancer Research.
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√ Diabetes Mellitus And Hypertension Associated With Shock Wave Lithotripsy Of Renal And Proximal Ureteral Stones At 19 Years Of Follow-Up
Tuesday, 27 June 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Beware! Shock wave lithotripsy (SWL) for renal calculi patients may increase the risk of hypertension and diabetes in long-term follow-up.
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√ Review Identifies Factors That Influence Patient Treatment Choice For Localized Prostate Cancer
Friday, 12 May 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Variables that influence a patients' choice of treatment for localized prostate cancer (CaP) are identified in a literature review that is authored by Dr. Zeliadt and colleagues and appears in the on-line version of Cancer, 2006.
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√ Article Examines The Use Of A Running Vesicourethral Anastomosis Suture In Minilaparotomy Radical Retropubic Prostatectomy
Thursday, 27 April 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - The radical retropubic prostatectomy (RRP) performed via a minilaparotomy (using a 6-cm midline incision) is an attempt to improve on the post-operative discomfort that is seen with a standard RRP.
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√ The 'Learning Curve' In Hypospadias Surgery
Wednesday, 12 April 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - It has always been my opinion that successful hypospadias surgery is truly a reflection of surgeon experience.
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√ Study Uses Nanoparticles To Kill Cancer Cells
Tuesday, 11 April 2006
√ Editor's Pick: WASHINGTON (Reuters) - Researchers have found a way to target cancer cells by injecting tiny particles that will attack only the diseased cells while leaving healthy cells unscathed, according to a study released on Monday.
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√ Usage And Outcomes Of Primary Androgen Deprivation Therapy For Localized Prostate Cancer
Monday, 10 April 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - In the online March 2006 version of Cancer, Dr. Kawakami and associates report from the CaPSURE database that primary androgen deprivation therapy (PADT) is used in 14% of prostate cancer (CaP) patients with reasonable outcomes at approximately 5 years follow-up.
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√ Genetic Polymorphism In An Estrogen Receptor Gene Associated With Prostate Cancer Risk
Friday, 07 April 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - The second estrogen receptor (beta) is highly expressed in prostatic epithelium.
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√ Underutilization Of Partial Nephrectomy For Localized Renal Cell Carcinoma In The United States
Wednesday, 29 March 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - In the past, the gold standard for the treatment of localized renal tumors has been radical nephrectomy.
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√ Clinical Significance Of Primary Vesicoureteral Reflux And Urinary Antibiotic Prophylaxis After Acute Pyelonephritis: A Multicenter, Randomized, Controlled Study
Friday, 24 March 2006
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√ Computerized Tomography Guided Percutaneous Renal Cryoablation With The Patient Under Conscious Sedation: Initial Clinical Experience
Monday, 20 March 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - When an event occurs once, we have a tendency to look at it as a phenomenon, but when it occurs twice, it begins to enter the realm of accepted reality.
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√ An Argument For The Use Of Zoledronic Acid In Androgen-Sensitive Prostate Cancer
Monday, 20 March 2006
√ Editor's Pick:
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√ Thrombocytosis: A Clinical Marker Of Tumor Aggressiveness In Renal Cell Carcinoma
Wednesday, 15 March 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Molecular and serum markers of prognosis in renal cell carcinoma have remained elusive.
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√ Partial Nephrectomy: Urologists Need To Practice What We Preach
Tuesday, 14 March 2006
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√ Role of Thalidomide and Subcutaneous Interleukin 2 in Metastatic Renal Cell Carcinoma: Results of Two Clinical Trials
Thursday, 09 March 2006
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√ Primary Vesicoureteral Reflux Detected In Neonates With A History Of Fetal Renal Pelvis Dilatation: A Prospective Clinical And Imaging Study
Wednesday, 08 March 2006
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√ Satisfaction And Failure Rates Of Artificial Urinary Sphincter Similar In Men And Women
Thursday, 02 March 2006
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√ Nutritional Antioxidants And Prostate Cancer Risk
Tuesday, 28 February 2006
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√ Randomized Trial Of Saw Palmetto Versus Placebo Published In New England Journal Of Medicine Suggests No Benefit
Thursday, 23 February 2006
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√ Where Have All The Nephrectomies Gone? Regionalization Of Complex Urologic Surgical Procedures
Thursday, 16 February 2006
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√ Laparoscopic Partial Nephrectomy: The Evolution Continues?..
Wednesday, 08 February 2006
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√ Using Imaging To Differentiate Papillary Renal Cell Carcinoma From Clear Cell Renal Cell Carcinoma: Perioperative Implications
Thursday, 02 February 2006
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√ Local Cost Structures And The Economics Of Robot Assisted Radical Prostatectomy
Tuesday, 24 January 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - The authors have nicely demonstrated that in order to begin to reach fiscal benefit with the da Vinci robotic prostatectomy, a hospital may need to have at least 7 robotic prostatectomies done per week with a length of stay of just over 1 day (i.e. < 36 hours).
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√ Women's First Pregnancy And Delivery Creates Risk For Stress Urinary Incontinence (SUI)
Tuesday, 24 January 2006
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√ The Role Of Percutaneous Biopsy For The Indeterminant Renal Mass Revisited
Thursday, 19 January 2006
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√ Erectile Dysfunction Strongly Predicts For Subsequent Cardiovascular Disease
Wednesday, 11 January 2006
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√ Endorectal MRI Shown Useful in Predicting Need for Third Prostate Biopsy in Some Patients
Friday, 10 October 2003
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√ Herbal COX-2 Inhibitor Induces Prostate Cancer Cell Apoptosis
Tuesday, 29 July 2003
√ Editor's Pick: NEW YORK (Reuters Health) - Zyflamend, an herbal extract, inhibits cyclooxygenase-2 and causes in vitro apoptosis of a human prostate cancer cell line, according to a report at the Society of Urologic Oncology meeting at the NIH in Bethesda, Maryland.
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√ PSA Resting May be Less Sensitive Than Previously Thought
Wednesday, 23 July 2003
√ Editor's Pick: NEW YORK (Reuters Health) - The sensitivity of the prostate-specific antigen (PSA) test appears to be lower than previous analyses have suggested, according to a report in the July 24th issue of The New England Journal of Medicine.
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√ PSA Precursor More Cancer-specific Than Other Markers
Tuesday, 15 July 2003
√ Editor's Pick:
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