ASCO 2006 - GU Oral Presentation: Testicular Cancer
Tuesday, 06 June 2006
Three abstracts were presented at this session with the focus on imaging in the management of testicular germ cell tumors.
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AUA 2006 - Contemporary Results For Stage I RPLND Less Morbid Than Historical Controls
Monday, 22 May 2006
Abstract 586 Beck and colleagues from Indiana performed a review of 73 patients who underwent primary RPLND in the last 2 years to assess short term morbidity.
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AUA 2006 - One Third Of Patients With Residual Masses After Chemotherapy Will Have Disease Outside The Modified Template: The Case For A Bilateral Template Dissection
Monday, 22 May 2006
Abstract 593
Carver et al from Memorial Sloan-Kettering presented data from 532 patients who underwent postchemotherapy RPLND for testis cancer.
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AUA 2006 - Oncological Efficacy Of Laparoscopic RPLND: A Multi-Institutional Review
Monday, 22 May 2006
Abstract 587
Data from 3 institutions were reviewed to assess the recurrence patterns of 143 patients who underwent laparoscopic RPLND for Stage I disease.
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Risk Of Secondary Malignancies In Testicular Cancer: Data From Over 40,000 Survivors
Thursday, 27 April 2006
BERKELEY, CA (UroToday.com) - While in the United States the preferred treatment for stage I mixed germ cell tumors has been retroperitoneal lymphadenectomy, adjuvant chemotherapy has been more commonly used in Europe.
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Single-Dose Carboplatin Comparable To Prophylactic Radiotherapy For Stage I Seminoma: Results Of A Randomized Trial
Thursday, 13 April 2006
BERKELEY, CA (UroToday.com) - The risk of relapse for patients with stage I seminoma has traditionally ranged between 10 and 15%, depending on the local pathological characteristics of the tumor.
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Cardiovascular Risk Elevated In Testicular Cancer Survivors
Friday, 17 February 2006
NEW YORK (Reuters Health) - Survivors of nonseminomatous testicular cancer have a moderately increased risk of myocardial infarction at young ages, according to Dutch researchers.
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Ask The ASCO Expert Events In March On PLWC
Friday, 03 February 2006
During the month of March, the American Society of Clinical Oncology's
(ASCO) patient information website, People Living With Cancer (www.plwc.org) will host two Ask the ASCO Expert events.
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Risk Adapted Management of Clinical Stage I Seminoma
Tuesday, 24 January 2006
BERKELEY, CA (UroToday.com) - The standard therapy for stage I seminoma has long been radical orchiectomy followed by radiation therapy to the retroperitoneal and ipsilateral pelvic lymph nodes to a dose of 20-25 Gy, with a recurrence rate in the range of 3-5%, with virtually all recurrences occurring outside of the radiation portal.
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Individualized Treatment May Be Best In Seminoma
Wednesday, 11 January 2006
NEW YORK (Reuters Health) - Individually tailored (risk-adapted) treatments rather than systematic approaches may be the optimal means of managing patients with stage 1 seminoma, according to Spanish researchers.
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Paternity Rates Following Testis Cancer: Impact Of therapy On Post-Treatment Conception
Thursday, 08 December 2005
BERKELEY, CA (UroToday.com) - Subfertility/infertility has been associated with both the diagnosis of testis cancer as well as with subsequent curative therapy.
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Greater Testicular Cancer Risk Seen In Infertile Men
Tuesday, 22 November 2005
NEW YORK (Reuters Health) - Men presenting for infertility treatment are 20 times more likely than men in the general population to be diagnosed with testicular cancer, a new study shows.
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Histology At Retroperitoneal Lymphadenectomy For Stage B1 Disease Does Not Predict
Thursday, 03 November 2005
BERKELEY, CA (UroToday.com) - Pathologic stage B1 testes cancer is defined as a lymph node mass
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Paternity Often Possible After Treatment For Testicular Cancer
Wednesday, 02 November 2005
NEW YORK (Reuters Health) - New research indicates that an overall paternity rate of 71% can be achieved after treatment for testicular cancer. However, the type of treatment has a strong impact on the rate and how long it will take to conceive.
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What Is The Risk Of Testicular Cancer In A Patient With Infertility?
Wednesday, 26 October 2005
BERKELEY, CA (UroToday.com) - The lower fertility potential of patients diagnosed with testicular cancer is well established.
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Long Term Survivors Of Testicular Cancer Have An Increased Risk Of Developing A Second Solid Cancer
Monday, 24 October 2005
BERKELEY, CA (UroToday.com) - Second primary cancers have emerged as a leading cause of death in long term testicular cancer survivors, but the risk of actually developing these cancers remains unclear.
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Indiana University Study Shows Desperation Retroperitoneal Lymphadenectomy For Testes Cancer Results In A 54% Cure Rate
Tuesday, 04 October 2005
BERKELEY, CA (UroToday Inc.) - It is generally viewed that elevated testes cancer tumor markers following chemotherapy indicate the need for more chemotherapy.
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Testicular Cancer Survivors Face Long-Term Increased Risk Of Second Cancer
Thursday, 22 September 2005
NEW YORK (Reuters Health) - Men who survive testicular cancer are at increased risk of developing other types of cancer for at least 35 years after being diagnosed with the original disease, a new analysis shows.
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Testicular Cancer Risk Linked With Maternal Weight
Wednesday, 24 August 2005
NEW YORK (Reuters Health) - The results of a study published in the August 20th issue of the International Journal of Cancer suggest an association between maternal weight at the time of delivery and a subsequent increased risk of testicular cancer in adult male offspring.
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Single-Dose Carboplatin As Effective As Radiotherapy For Stage I Seminoma
Monday, 25 July 2005
NEW YORK (Reuters Health) - Adjuvant radiation therapy appears to be no better than one dose of carboplatin in preventing relapse of stage I seminomatous germ-cell tumors following hemiorchidectomy, a multinational team reports.
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Risk Of Contralateral Testicular Cancer Appears Low
Thursday, 21 July 2005
NEW YORK (Reuters Health) - Although the risk of a second metachronous cancer of the testicles is elevated following diagnosis of a first, the overall risk is low and survival remains high, study results show.
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Testicular Cancer on the Rise in Much of the World
Thursday, 30 June 2005
NEW YORK (Reuters Health) - Though testicular cancer remains relatively uncommon, rates of the disease have risen in many countries since the 1970s, a new study shows.
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Fertility Preservation Can Offer Options For Cancer Patients
Tuesday, 21 June 2005
NEW YORK (Reuters Health) - Cancer patients should be informed of the options for fertility preservation and future reproduction before undergoing cancer treatments, according to a report in the June issue of Fertility and Sterility.
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Testicular Cancer Survivors at Increased Risk for the Metabolic Syndrome
Thursday, 09 June 2005
NEW YORK (Reuters Health) - In long-term survivors of testicular cancer, alterations in testosterone may play a role in the development of the metabolic syndrome, Danish investigators report.
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Anxiety Common Among Testicular Cancer Survivors
Friday, 29 April 2005
NEW YORK (Reuters Health) - Long-term survivors of testicular cancer appear to be at increased risk of anxiety disorder, Norwegian researchers report in the April 1st issue of the Journal of Clinical Oncology.
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In Randomized Study of Patients with Localized Cancer and DVT, Low Molecular Weight Heparin found to offer Survival Advantage over Coumarin Derivatives
Friday, 15 April 2005
BERKELEY, CA (UroToday Inc.) - Without question, patients with cancer at a higher risk for thromboembolic events. Until very recently, the decision to place a patient with deep vein thrombosis (DVT) on coumarin or low molecular weight heparin was largely based on drug cost or patient convenience.
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Decreasing Adjuvant Radiotherapy from 30 to 20Gy in Stage I Testicular Seminoma Reduces Morbidity without Sacrificing Efficacy
Friday, 08 April 2005
BERKELEY, CA (UroToday Inc.) - Patients presenting with clinical stage I seminoma are understaged in up to 20% of cases.
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Long-term Outcome of Postorchiectomy Surveillance for Stage I Testicular Seminoma
Thursday, 24 March 2005
BERKELEY, CA (UroToday Inc.) - Advances in the quality of cross-sectional imaging and systemic chemotherapy for testicular cancer have significantly expanded the treatment options for localized testicular cancer.
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Adjuvant Radiotherapy Dose for Stage I Seminoma: Medical Research Council/EORTC Randomized Trial Shows Decreased Morbidity and Equal Efficacy for 20 Gy compared with 30Gy
Thursday, 10 March 2005
BERKELEY, CA (UroToday Inc.) - Over 75% of patients with testicular seminoma present with stage I disease. Since relapse rates approach 15%, these patients have traditionally been treated with adjuvant retroperitoneal radiation.
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Scientists Find Marker for Early Testicular Cancer
Thursday, 03 March 2005
LONDON (Reuters) - Danish scientists said on Thursday they had discovered a new method that could help to detect very early signs of testicular cancer.
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Early Predicted Time to Normalization of Tumor Markers Predicts Outcome in Poor-Prognosis Nonseminomatous Germ Cell Tumors
Friday, 19 November 2004
BERKELEY, CA (UroToday Inc.) - The integration of cisplatin-based chemotherapy and surgery into the first-line treatment of disseminated nonseminomatous germ cell tumors (NSGCT) has resulted in cure rates of approximately 80% during the past two decades.
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Elderly Patients Underrepresented in Trials of New Cancer Drugs
Wednesday, 17 November 2004
NEW YORK (Reuters Health) - New research indicates that cancer patients over 65 years of age are underrepresented in registration trials of new cancer agents.
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PEB Chemotherapy Provides Excellent Event-free Survival with Minimal Toxicity in Children with Malignant Germ Cell Tumors
Monday, 25 October 2004
BERKELEY, CA (UroToday Inc.) - Survival in children with malignant germ cell tumors (MGCT) has improved significantly with the advent of multimodal therapy. Introduction of cisplatin, etoposide and bleomycin (PEB) chemotherapy in adults with testicular MGCT has dramatically improved outcomes.
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Whole Body MRI Rapidly Scans for Metastases
Thursday, 14 October 2004
NEW YORK (Reuters Health) - The results of whole body magnetic resonance imaging (MRI) compare well with other methods of evaluating metastases and can be done rapidly, German researchers report in the October issue of Radiology.
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Risk of Testicular, Kidney and Bladder Cancer is not Increased With Exposure to Diesel or Gasoline Engine Exhaust
Thursday, 26 August 2004
BERKELEY, CA (UroToday Inc.) - Engine exhaust is potentially carcinogenic to humans. While evidence from animal studies suggests this, epidemiologic studies have provided limited evidence, mainly implicating only lung and bladder cancer.
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Physical Symptoms Predict Survival Time in Terminal Cancer
Tuesday, 27 July 2004
NEW YORK (Reuters Health) - Physical symptoms that affect health-related quality-of-life (QOL), such as nausea and dyspnea, appear to be associated with shorter survival in terminal cancer patients, researchers report in the July 26th online edition of Cancer.
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Prince Told "You Got it Wrong" on Cancer
Friday, 09 July 2004
LONDON (Reuters Health) - The heir to the British throne got a stern telling-off by a leading physician this week over his support for alternative cancer therapies.
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Quality of Life for Cancer Patients May Be All in the Genes
Thursday, 10 June 2004
NEW ORLEANS (Reuters Health) - The results of a new study provide preliminary evidence of a "potentially strong and specific" relationship between the genetic makeup of cancer patients and their quality of life (QOL) during cancer treatment.
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Adjuvant Single-shot Carboplatin Equal to Radiotherapy in Early Seminoma
Wednesday, 09 June 2004
NEW ORLEANS (Reuters Health) - Results of a randomized study indicate that a single course of intravenous carboplatin given over one day is as effective as a several week course of radiation therapy (RT) in the adjuvant treatment of stage I seminoma of the testis after orchidectomy.
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Baby Boy Born From Sperm Frozen Record 21 Years
Wednesday, 26 May 2004
LONDON (Reuters) - A baby boy was born after being conceived with sperm frozen 21 years earlier in what scientists said Tuesday was a new record.
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Smoking During Pregnancy Linked with Testicular Cancer Risk in Offspring
Wednesday, 12 May 2004
NEW YORK (Reuters Health) - Analyses of data from cancer registries and published surveys in Europe suggest that maternal smoking during pregnancy increases male offspring's risk of testicular cancer, according to epidemiologists in Sweden and Italy.
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Cancer Trial Participants Rarely Told of Results
Wednesday, 21 April 2004
NEW YORK (Reuters Health) - Cancer patients who participate in clinical trials are often left in the dark about the results of the studies, according to a new report.
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Laparoscopic Retroperitoneal Lymph Node Dissection Shows Good Long-Term Oncologic Performance with Less Morbidity
Monday, 12 April 2004
Retroperitoneal lymph node dissection (RPLND) is a commonly accepted diagnostic and therapeutic option in patients with Stage I and Stage II non-seminomatous testicular cancer (NSGCT).
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New Tumor Classification Scheme Unlinks Tumor Type From Tumor Site
Wednesday, 24 March 2004
NEW YORK (Reuters Health) - A radically different new system for classification of tumors has been set forth by a National Cancer Institute official.
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Aprepitant Regimen Sustains Antiemetic Effect Over Multiple Chemotherapy Cycles
Tuesday, 23 March 2004
NEW YORK (Reuters Health) - The addition of the drug aprepitant to other antiemetic therapy is associated with less nausea and vomiting during an initial cycle of chemotherapy, and the response is maintained well during subsequent cycles, investigators report.
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Excess Mortality Risk Increases Over Time in Seminoma Survivors
Thursday, 11 March 2004
NEW YORK (Reuters Health) - The risk of death from heart disease or second cancer rises significantly above that of the general population 15 years after treatment for testicular seminoma with orchiectomy and radiation therapy, report physicians at the University of Texas M.D. Anderson Cancer Center in Houston.
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Alternative Therapies Popular with Cancer Patients
Tuesday, 24 February 2004
NEW YORK (Reuters Health) - Insured cancer patients in the State of Washington are considerably more likely to use complementary and alternative medical providers than are insured patients without the disease, researchers report in the February 23rd online edition of Cancer.
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Careful Open Resection of Genital Branch of Genito-Femoral Nerve Relieves Chronic Post-herniorrophy Testicular Pain
Monday, 16 February 2004
Chronic scrotal and testicular pain represent objectionable side effects of inguinal herniorrophy surgery.
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Cancer Web Sites No Aid to Trial Enrollment
Tuesday, 10 February 2004
NEW YORK (Reuters Health) - Web sites for organizations involved in clinical cancer research lack sufficient information to enhance patient enrollment in clinical trials, according to a report in the February 9th online edition of Cancer.
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Long-Term Survival After High-Dose Salvage Chemotherapy for Germ Cell Malignancies with Adverse Prognostic Variables
Monday, 02 February 2004
BERKELEY, CA (UroToday Inc.) - Testis cancer remains the paradigm of success in the treatment of solid malignancies. Approximately 70% of patients with metastatic testicular cancer are cured with their initial cisplatin-based combination chemotherapy. However, 30% of patients fail and will require salvage therapy.
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Testicular Cancer 
