AUA 2006 - Complications of MR-Guided Percutaneous Renal Cryoablation
Sunday, 21 May 2006
Moderate Poster Session Saturday, May 20, 2006 1:00 PM - 3:00 PM.
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AUA 2006 - Preoperative And Intraoperative Features Associated With Positive Lymph Nodes During Nephrectomy For Renal Cell Carcinoma
Sunday, 21 May 2006
R. H. Thompson, C. M. Lohse, I. Frank, H. Zincke, M. L. Blute, and B. C. Leibovich.
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AUA 2006 - Enucleation Of Renal Cell Carcinoma With Ablation Of Tumor Base: Is Cancer Control Comparable To Partial Nephrectomy?
Sunday, 21 May 2006
A. Kutikov, L. K. Fossett, T. J. Guzo, A. J. Wein, K. N. Vanarsdalen, and S. B. Malkowicz.
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AUA 2006 - Society of Urologic Oncology Meeting: Partial Nephrectomy and Kidney Update
Saturday, 20 May 2006
The annual meeting of the Society of Urologic Oncology took place on Saturday, May 20, 2006 during the annual American Urological Association Meeting in Atlanta, Georgia. In the afternoon session, Dr. Brad Leibovich, Mayo Clinic moderated a session titled "Partial Nephrectomy and Kidney Update".
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Role Of Partial Nephrectomy In The Treatment Of Upper Tract Transitional Cell Carcinoma
Friday, 19 May 2006
BERKELEY, CA (UroToday.com) - Traditionally, upper tract transitional cell carcinoma (TCC) is managed with nephroureterectomy with excision of a bladder cuff. In cases of locally advanced or regionally advanced disease, neoadjuvant systemic chemotherapy may be offered prior to surgery.
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Renal Cell Carcinoma In The Pediatric Population
Monday, 15 May 2006
BERKELEY, CA (UroToday.com) - While the incidence of renal cell carcinoma (RCC) is rising, it remains a relatively uncommon malignancy in the pediatric population, where it represents only 2-6% of solid renal malignancies. In this report, Cook and colleagues describe their experience with the management of RCC in childhood, specifically examining the role of partial nephrectomy as a reasonable surgical approach in patients with anatomically amenable tumors.
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Inhibition Of DNA Methyltransferase 1 Activity With The Antisense Oligonucleotide MG98 In Patients With Metastatic Renal Cell Carcinoma (RCC): A phase II Trial
Thursday, 11 May 2006
BERKELEY, CA (UroToday.com) - Despite recent advances in the treatment of patients with metastatic RCC, the overall prognosis is dismal and new therapies must be investigated to improve patient outcome.
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The Management Of Renal Cell Carcinoma In The Elderly: Physiologic Age Wins Out Over Chronologic Age
Wednesday, 10 May 2006
BERKELEY, CA (UroToday.com) - The median age of presentation for patients with renal cell carcinoma (RCC) is in the 6th decade of life, but urologists are not uncommonly confronted with an elderly patient (≥75 years of age) with a renal mass seeking treatment. As the population ages, co-morbidities become more confounding in predicting patient outcome to therapy, and may influence the application of surgical therapy with curative intent to elderly patients. In this study by Berdjis and colleagues out of Germany, the outcome of elderly patients (defined as ≥75 years of age) is examined relative to a younger patient cohort.
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What Is The Best Laparoscopic Approach For Laparoscopic Radical Nephrectomy? A Randomize Prospective Trial Examines Hand-Assisted, Transperitoneal, And Retroperitoneal Approaches
Tuesday, 09 May 2006
BERKELEY, CA (UroToday.com) - Laparoscopic radical nephrectomy is rapidly becoming the gold standard as the surgical procedure of choice in patients with localized renal cell carcinoma. Many laparoscopic approaches exist, including hand assisted (HAL), transperitoneal (TPL), and retroperitoneal (RPL) techniques, each with its own benefits and drawbacks. Nadler and colleagues, out of Northwestern, compared each of these techniques in patients with T1 tumors in a prospective randomized trial.
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Circulating Tumor Cells In The Bone Marrow Of Patients With Metastatic Renal Cell Carcinoma May Be Prognostic Of Outcome
Monday, 08 May 2006
BERKELEY, CA (UroToday.com) - Circulating tumor cells in the blood and bone marrow have been examined in a variety of malignancies, including colorectal, breast, and head & neck cancers, to determine their prognostic significance. The cells are detected through cytokeratin (CK) antibody immunohistochemical staining. In a previous study, 256 patients with renal cell carcinoma (RCC) without evidence of distant metastases were examined for CK+ cells in bone marrow aspirates and no significant correlation with prognosis was found. In this study by Buchner and colleagues, the prognostic significance of CK+ tumor cells in the bone marrow aspirates of 55 patients with metastatic RCC was examined.
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BJUI Mini Reviews - Positron Emission Tomography (PET), Immuno-PET and Radioimmunotherapy in Renal Cell Carcinoma: A Developing Diagnostic and Therapeutic Relationship
Tuesday, 02 May 2006
This review investigates the use of PET/CT, and how it may alter the ability to detect pelvic and other small metastatic deposits, improving the sensitivity of staging and re-staging.
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CHMP Grants First Conditional Marketing Recommendation To Pfizer's Sutent
Monday, 01 May 2006
LONDON (Agence de Presse Medicale for Reuters Health) - Pfizer's orphan cancer drug Sutent (sunitinib malate) has become the first product to be recommended for conditional marketing authorisation, the European Medicines Agency said on Friday.
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Updated Statistics On The American Obesity Epidemic: Data From The CDC
Monday, 24 April 2006
BERKELEY, CA (UroToday.com) - The success of the fast food and soft drink industries has translated into an unprecedented rise in childhood and adult obesity.
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CORRECTION: Sunitinib Malate Shows Anti-Tumour Activity In Metastatic Renal Cell Carcinoma
Monday, 24 April 2006
PARIS (Reuters Health) - By simultaneously inhibiting all known vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) receptors and their pathways, sunitinib malate prolongs progression-free survival in patients with metastatic renal cell carcinoma (mRCC) refractory to cytokine therapy.
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Laparoscopic Partial Nephrectomy For Centrally Located Renal Tumors
Monday, 17 April 2006
BERKELEY, CA (UroToday.com) - The Cleveland Clinic Group has shown that with experience they have been able to effectively offer laparoscopic partial nephrectomy (LPN) to more patients with centrally located lesions.
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Single-Dose Carboplatin Comparable To Prophylactic Radiotherapy For Stage I Seminoma: Results Of A Randomized Trial
Thursday, 13 April 2006
BERKELEY, CA (UroToday.com) - The risk of relapse for patients with stage I seminoma has traditionally ranged between 10 and 15%, depending on the local pathological characteristics of the tumor.
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Partial Nephrectomy And Radical Nephrectomy Offer Similar Cancer Outcomes In Renal Cortical Tumors 4 cm Or Larger
Tuesday, 11 April 2006
BERKELEY, CA (UroToday.com) - Less is Just As Good. In this comparative study, 33 patients who underwent partial nephrectomy (PN) for renal tumors ≥ 4 cm were matched by tumor diameter, histology subtype, patient age and sex, to 2 patients who underwent radical nephrectomy (RN) for the same disease.
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Prolonged Survival Linked To Intravenous Vitamin C Seen In Three Cancer Patients
Tuesday, 11 April 2006
NEW YORK (Reuters Health) - Researchers at the National Institutes of Health and colleagues in Canada report three cases in which high-dose intravenously administered vitamin C apparently led to longer-than-expected survival in patients with advanced cancer. Two of them show long-term survival without evidence of disease.
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Sunitinib Malate Shows Anti-Tumour Activity In Metastatic Renal Cell Carcinoma
Tuesday, 11 April 2006
PARIS (Reuters Health) - By simultaneously inhibiting all known vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) receptors and their pathways, sunitinib malate prolongs progression-free survival in patients with metastatic renal cell carcinoma (mRCC) refractory to cytokine therapy.
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European Urology - Understanding the Importance of Smart Drugs in Renal Cell Carcinoma
Monday, 03 April 2006
Objective: To understand the mode of action of the currently most investigated
new drugs in renal cell carcinoma (RCC) and ultimately to analyze
what should be the role of the urologist in this new therapeutic era.
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Nexavar Approved In Switzerland For The Treatment Of Patients With Advanced Kidney Cancer
Thursday, 30 March 2006
WEST HAVEN, Conn. and EMERYVILLE, Calif., March 30 /PRNewswire-FirstCall/
-- Bayer Pharmaceuticals Corporation (NYSE: BAY) and Onyx Pharmaceuticals,
Inc. (Nasdaq: ONXX) today announced that the Swiss Agency for Therapeutic
Products (Swissmedic) has approved Nexavar(R) (sorafenib) tablets for the
treatment of patients with advanced renal cell carcinoma (RCC), or kidney
cancer, after nepherectomy and prior palliative or adjuvant therapy with
cytokines (IL-2, IFN).
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√ Underutilization Of Partial Nephrectomy For Localized Renal Cell Carcinoma In The United States
Wednesday, 29 March 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - In the past, the gold standard for the treatment of localized renal tumors has been radical nephrectomy.
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Obesity May Be Partly To Blame For Rising Rates Of Renal Cell Cancer
Wednesday, 22 March 2006
NEW YORK (Reuters Health) - Among women, obesity seems to increase the risk of renal cell cancer (RCC) regardless of the fat distribution pattern, research suggests, while among men, a small hip circumference is associated with increased risk.
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√ Computerized Tomography Guided Percutaneous Renal Cryoablation With The Patient Under Conscious Sedation: Initial Clinical Experience
Monday, 20 March 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - When an event occurs once, we have a tendency to look at it as a phenomenon, but when it occurs twice, it begins to enter the realm of accepted reality.
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No Advantage With Thalidomide For Metastatic Renal Cell Carcinoma
Friday, 17 March 2006
NEW YORK (Reuters Health) - Thalidomide is no more effective than medroxyprogesterone acetate for patients with metastatic renal cell carcinoma (RCC), and is more toxic, a new phase II/III study shows.
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The Biology Of Adrenal Metastases In Renal Cell Carcinoma
Thursday, 16 March 2006
BERKELEY, CA (UroToday.com) - Urologists have noted the apparent affinity of renal cell carcinoma (RCC) to metastasize to the adrenal gland, which has promoted many to advocate ipsilateral adrenalectomy at the time of surgical resection of the primary tumor.
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√ Thrombocytosis: A Clinical Marker Of Tumor Aggressiveness In Renal Cell Carcinoma
Wednesday, 15 March 2006
√ Editor's Pick: BERKELEY, CA (UroToday.com) - Molecular and serum markers of prognosis in renal cell carcinoma have remained elusive.
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√ Partial Nephrectomy: Urologists Need To Practice What We Preach
Tuesday, 14 March 2006
√ Editor's Pick:
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Renal And Extrarenal Predictors Of Nephrectomy From The National Trauma Data Bank Reviewed
Monday, 13 March 2006
BERKELEY, CA (UroToday.com) - The management of renal trauma has become increasingly conservative with multiple series showing renal preservation after high grade injury.
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Laparoscopic Partial Nephrectomy For Centrally Located Renal Tumors: Results In The Hands Of The Experts
Friday, 10 March 2006
BERKELEY, CA (UroToday.com) - In this article, the group from the Cleveland Clinic, who has arguably the largest experience with laparoscopic partial nephrectomy (LPN) by a single surgeon (Dr. Gill), now presents their results using this technique for centrally located renal tumors, defined as those tumors with direct contact of the pelvicaliceal system and/or renal sinus on preoperative imaging.
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√ Role of Thalidomide and Subcutaneous Interleukin 2 in Metastatic Renal Cell Carcinoma: Results of Two Clinical Trials
Thursday, 09 March 2006
√ Editor's Pick:
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Is There Any Role For Thalidomide As A Monotherapy In The Management Of Metastatic Renal Cell Carcinoma?
Wednesday, 08 March 2006
BERKELEY, CA (UroToday.com) - Thalidomide remains an enigma in the treatment of metastatic renal cell carcinoma (RCC).
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Percutaneous Cryoablation Helpful Against Renal Tumors
Wednesday, 08 March 2006
NEW YORK (Reuters Health) - Initial experience with computed tomography (CT)-guided percutaneous renal cryoablation suggests that the approach is effective in dealing with small non-centrally located tumors, according to a study appearing in the Journal of Urology for February.
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Is Partial Nephrectomy Oncologically Safe For Tumors Greater Than 4cm?
Tuesday, 07 March 2006
BERKELEY, CA (UroToday.com) - Traditionally, nephron sparing surgery in the presence of a normal contralateral kidney is primarily advocated for tumors ≤ 4cm.
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Activity Of Imatinib (Gleevec®) In Metastatic Renal Cell Carcinoma
Monday, 06 March 2006
BERKELEY, CA (UroToday.com) - Until recently, standard therapy for metastatic renal cell carcinoma (RCC) has been immunotherapy with either interleukin 2 or interferon.
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BJUI Mini Reviews - Management Approaches to Small Renal Tumours
Wednesday, 01 March 2006
This article reviews these methods for solid, enhancing renal masses consistent with RCC, and excluding angiomyolipomas
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BJUI Mini Reviews - Treatment Targeted at Vascular Endothelial Growth Factor: A PromisingApproach to Managing Metastatic Kidney Cancer
Wednesday, 01 March 2006
This article reviews the mechanism, toxicity and clinical efficacy of recent VEGF-targeted therapy in patients with metastatic RCC. inhibitors
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Total Nephrectomy Overused In Kidney Cancer
Wednesday, 22 February 2006
NEW YORK (Reuters Health) - Although partial nephrectomy may be appropriate for dealing with small renal masses, total nephrectomy appears to be the more usual surgical modality in the majority of such cancer patients, researchers report in the March issue of the Journal of Urology.
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√ Where Have All The Nephrectomies Gone? Regionalization Of Complex Urologic Surgical Procedures
Thursday, 16 February 2006
√ Editor's Pick:
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Obesity And Kidney Cancer: Body Mass Index Does Not Predict Survival Or Progression Free Survival In Patients Undergoing Surgery For Renal Cell Carcinoma
Tuesday, 14 February 2006
BERKELEY, CA (UroToday.com) - Epidemiologic studies have suggested a link between obesity and the development of kidney cancer.
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Chimeric Monoclonal Antibody WX-G250 And Interleukin 2: Results In Metastatic Renal Cell Carcinoma
Friday, 10 February 2006
BERKELEY, CA (UroToday.com) - WX-G250 is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, an antigen expressed in 95% of clear cell renal cell carcinomas (RCC).
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√ Laparoscopic Partial Nephrectomy: The Evolution Continues?..
Wednesday, 08 February 2006
√ Editor's Pick:
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Making Laparoscopic Partial Nephrectomy Easier: Tricks Of The Trade
Tuesday, 07 February 2006
BERKELEY, CA (UroToday.com) - Laparoscopic partial nephrectomy can be a daunting procedure even for the most experienced laparoscopic surgeon.
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Complications After Percutaneous Radiofrequency Ablation Of Renal Tumors
Monday, 06 February 2006
BERKELEY, CA (UroToday.com) - While the newer, less invasive treatment modalities for renal tumor disease offer many advantages to patients, it is important reports such as this from Duke University, that help the clinician determine the appropriateness of this treatment for the individual patient.
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High Intensity Focused Ultrasound Therapy For Renal Tumors: Not Even Close To Being Ready For Primetime!
Friday, 03 February 2006
BERKELEY, CA (UroToday.com) - Some researchers estimate that the incidence of asymptomatic renal tumors ≤ 3cm currently being detected are in the range of 10-40% of all renal masses undergoing treatment.
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Ask The ASCO Expert Events In March On PLWC
Friday, 03 February 2006
During the month of March, the American Society of Clinical Oncology's
(ASCO) patient information website, People Living With Cancer (www.plwc.org) will host two Ask the ASCO Expert events.
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√ Using Imaging To Differentiate Papillary Renal Cell Carcinoma From Clear Cell Renal Cell Carcinoma: Perioperative Implications
Thursday, 02 February 2006
√ Editor's Pick:
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The Problem Of Minimal Fat Angiomyolipomas: Can Imaging Be Used To Identify These Lesions To Reduce Therapeutic Morbidity?
Wednesday, 01 February 2006
BERKELEY, CA (UroToday.com) - Angiomyolipoma (AML) of the kidney is classically a radiographic diagnosis characterized by the presence of fat. Indications for surgical therapy include size > 4cm, symptoms (hemorrhage, pain), or equivocal radiographic findings that cannot rule out renal cell carcinoma (RCC).
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Targeted Therapy Represents A Significant Advance In The Treatment of Metastatic Renal Cell Carcinoma: Results Of A Phase II Multicenter Trial With SU11248 (Sunitinib Malate)
Tuesday, 31 January 2006
BERKELEY, CA (UroToday.com) - SU11248 (sunitinib malate, Sutent) is a small molecule tyrosine kinase inhibitor that targets VEGF and PDGF receptors. This molecule was developed as a consequence of a further understanding of the biology of renal cell carcinoma (RCC) gained through identification of the VHL gene, which is mutated or silenced in >70% of sporadic clear cell RCC.
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Pediatric Renal Cell Carcinoma: A Rare Tumor With A Different Biology From That Seen In Adult Patients. The Boston Children?s Hospital Experience
Monday, 30 January 2006
BERKELEY, CA (UroToday.com) - While tumors of the kidney represent a relatively common pediatric malignancy, renal cell carcinoma (RCC) is relatively rare in the pediatric population, with Wilm's tumor representing the majority of primary renal malignancies.
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Renal Cancer 
