Matritech’s NMP22® BladderChek® Test will be Featured in Presentations at the American Urological Association (AUA) Annual Meeting
Monday, 14 May 2007
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Isothiocynate Intake Associated with a Decreased Risk of Bladder Cancer
Friday, 11 May 2007
BERKELEY, CA (UroToday.com) - Isothiocyanates (ITC) are compounds found in cruciferous vegetables such as broccoli, cauliflower, kale, turnips, collards, Brussels sprouts, cabbage, radish, turnip and watercress.
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Matrix Metalloproteinase Polymorphisms Are Associated with Bladder Cancer Invasiveness
Wednesday, 09 May 2007
BERKELEY, CA (UroToday.com) - While early cystectomy is indicated in select patients with polychronotropic stage Ta, T1, and CIS bladder cancer, the standard of care to prevent tumor progression for these patients continues to be intravesical BCG.
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Survivin Expression is Associated with Bladder Cancer Presence, Stage, Progression, and Mortality
Monday, 07 May 2007
BERKELEY, CA (UroToday.com) - Survivin is a member of the Inhibitors of Apoptosis (IAP) groups of proteins, which are known to contribute to the cell death 'escape' mechanisms of various cancer cells, including bladder cancer.
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The Modern Management of Upper Urinary Tract Urothelial Cancer: Tumour Diagnosis, Grading and Staging
Friday, 04 May 2007
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The Modern Management of Upper Tract Urothelial Cancer: Surgical Treatment
Thursday, 03 May 2007
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BJUI Mini Reviews - The Modern Management of Upper Tract Urothelial Cancer:
Tuesday, 01 May 2007
In this article we review current concepts and oncological outcomes of the surgical management of UUT-TCC considering recent technical developments. Is the standard RNU still necessary? Can organ- sparing techniques be used safely?
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BJUI Mini Reviews - The Modern Management of Upper Urinary Tract Urothelial Cancer:Tumour Diagnosis, Grading and Staging
Tuesday, 01 May 2007
Despite these limitations, endoscopic treatment in well selected patients is appropriate, and itsprecise role is currently being defined asexperience accumulates.
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BJUI Mini Reviews - Upper Urinary Tract Transitional Cell Carcinoma: Current Treatment Overview of Minimally Invasive Approaches
Tuesday, 01 May 2007
In this review weexamine the place of newer methods of treatment.
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 Podcast - Chemotherapy For High-Risk Disease At RRP
Thursday, 26 April 2007
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San Francisco Firefighters Cancer Prevention Foundation Spearheads Campaign Calling for Action to Address Firefighters Increased Risk for Cancer - Bladder Cancer Screening is the First Program Underway
Wednesday, 25 April 2007
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Matritech's NMP22(R) BladderChek(R) Test Being Used in Screening
Wednesday, 25 April 2007
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Society of Urologic Nurses and Associates Releases Guide for Nurses New to Operating Room
Tuesday, 24 April 2007
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European Urology - Histologic Grading of Noninvasive Papillary Urothelial Neoplasms
Monday, 02 April 2007
Volume 51, Issue 4, Pages 889-898 (April 2007)
Abstract -
Objectives:
In 1998, a revised system of classifying noninvasive papillary urothelial neoplasms of the urinary bladder was proposed and subsequently formally adopted by the World Health Organization (WHO).
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European Urology - Prepubic Urethrectomy during Radical Cystoprostatectomy
Monday, 02 April 2007
Volume 51, Issue 4, Pages 915-921 (April 2007)
Abstract -
Objectives:
In muscle-invasive bladder cancer, the risk of developing a urethral recurrence after cystectomy varies between 4% and 18%, especially when an ileal conduit is performed.
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European Urology - Short-Schedule Intravesical Gemcitabine with Ablative Intent in Recurrent Ta–T1, G1–G2, Low- or Intermediate-Risk, Transitional Cell Carcinoma of the Bladder
Monday, 02 April 2007
Volume 51, Issue 4, Pages 956-961 (April 2007)
Abstract -
Objectives:
Primary objective: to assess ablative efficacy and tolerability of short-schedule intravesical gemcitabine for intact, low- and intermediate-risk, recurrent superficial bladder tumours.
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European Urology - A Chemosensitivity Test for Superficial Bladder Cancer Based on Three-Dimensional Culture of Tumour Spheroids
Monday, 02 April 2007
Volume 51, Issue 4, Pages 962-970 (April 2007)
Abstract -
Objectives:
Three-dimensional (3D) spheroids are a good model for studying in vitro chemosensitivity because they reproduce unicellular and multicellular mechanisms of drug resistance.
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Implications of Statin Therapy in Bladder Cancer Patients
Thursday, 29 March 2007
BERKELEY, CA (UroToday.com) - Smoking is one of the major risk factors for the development of bladder cancer and is also associated with cardiac disease, hyperlipidemia, and atherosclerosis.
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EAU 2007 - Management of Superficial Urothelial Tumors
Thursday, 29 March 2007
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EAU 2007 - Debate - Plenary Session
Wednesday, 28 March 2007
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FDA Strengthens Safety Information for Erythropoiesis-Stimulating Agents (ESAs)
Wednesday, 14 March 2007
BERKELEY, CA (UroToday.com) - On March 9, 2007, the Food and Drug Administration issued a safety warning for all erythropoiesis-stimulating agents
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European Urology - Advanced Age Is Associated with Poorer Bladder Cancer-Specific Survival in Patients Treated with Radical Cystectomy
Wednesday, 14 March 2007
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Improved Detection and Surveillance of Bladder Cancer Using a Point-of-Care NMP22 Assay
Monday, 12 March 2007
BERKELEY, CA (UroToday.com) - "Bladder cancer continues to be a significant cause of morbidity and mortality.
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European Urology - Prognostic Markers for Bladder Cancer – Are We There Yet?
Thursday, 01 March 2007
Volume 51, Issue 3, Pages 591-592 (March 2007)
Invasive bladder cancer is a potentially lethal disease. Prognostic markers predicting outcome are clearly needed.
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RECAP FROM SE AUA PRESENTATION BY GIORA KATZ, MD
Thursday, 01 March 2007
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European Urology - Utility of Fluorescence In Situ Hybridization as a Non-invasive Technique in the Diagnosis of Upper Urinary Tract Urothelial Carcinoma
Friday, 23 February 2007
Volume 51, Issue 2, Pages 409-415 (February 2007)
Abstract -
Objectives:
To assess the clinical utility of a fluorescence in situ hybridization (FISH) assay as a non-invasive method for diagnosing and monitoring urothelial carcinoma (UC) in the upper urinary tract (UUT).
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European Urology - Synthetic Nucleic Acids as Potential Therapeutic Tools for Treatment of Bladder Carcinoma
Friday, 16 February 2007
Volume 51, Issue 2, Pages 315-327 (February 2007) Abstract - Objectives: Abnormal gene activation in human tumours including bladder cancers (bCAs) may cause altered proliferation, maturation, and apoptosis as well as development of resistance to therapeutic interventions.
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Advanced Age Is Associated with Poorer Bladder Cancer-Specific Survival in Patients Treated with Radical Cystectomy
Thursday, 15 February 2007
BERKELEY, CA (UroToday.com) - Traditional wisdom taught in urological residency has been that healthy octogenarians with bladder cancer may be offered radical cystectomy without a significantly increased incidence of postoperative complications.
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Spectrum Pharmaceuticals Announces Successful Completion of Patient Accrual in Its EOquin(R) Pilot Study, Prior to Initiating Phase 3 Studies in the U.S.
Tuesday, 13 February 2007
IRVINE, CA (Press Release) - Feb. 6 - Spectrum Pharmaceuticals (Nasdaq: SPPI) announced today that the Company has completed patient accrual in the U.S. pilot safety study of EOquin(R) in patients with noninvasive bladder cancer.
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European Urology - Perioperative Complications of Radical Cystectomy in a Contemporary Series
Tuesday, 13 February 2007
Volume 51, Issue 2, Pages 397-402 (February 2007) Abstract - Objectives: Radical cystectomy is the preferred standard treatment for patients with muscle-invasive bladder cancer. With improvements in intra- and perioperative care lower complication rates have been reported.
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European Urology - Gene Expression Analysis for the Prediction of Recurrence in Patients with Primary Ta Urothelial Cell Carcinoma
Thursday, 08 February 2007
Volume 51, Issue 2, Pages 416-423 (February 2007) Abstract - Objectives: The individual recurrence-free period after primary surgery of patients with Ta urothelial cell carcinoma (UCC) cannot be predicted accurately.
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European Urology - Advanced Age Is Associated with Poorer Bladder Cancer-Specific Survival in Patients Treated with Radical Cystectomy
Monday, 05 February 2007
Volume 51, Issue 3, Pages 699-708 (March 2007) Abstract - Objective:Bladder cancer (BCa) is a disease of older persons, the incidence of which is expected to increase as the population ages.
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European Urology -Validation of the Diagnostic Value of NMP22® BladderChek® Test as a Marker for Bladder Cancer by Photodynamic Diagnosis
Friday, 02 February 2007
Volume 51, Issue 2, Pages 403-408 (February 2007)
Abstract -
Objectives:
The aim of the present study was to validate the sensitivity and specificity of the new “point-of-care” NMP22® BladderChek® test compared to photodynamic diagnosis (PDD).
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Contribution of 11C-Choline Positron Emission Tomography/Computerized Tomography to Preoperative Staging of Advanced Transitional Cell Carcinoma
Friday, 02 February 2007
BERKELEY, CA (UroToday.com) - The SWOG neoadjuvant trial published in the New England Journal of Medicine in 2003 suggested that select patients with locally advanced bladder cancer might benefit from chemotherapy before surgery.
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European Urology - Hydronephrosis as a Prognostic Marker in Bladder Cancer in a Cystectomy-Only Series
Thursday, 01 February 2007
Volume 51, Issue 3, Pages 690-698 (March 2007)
1. Introduction
Hydronephrosis is a common finding in patients with bladder carcinoma. The incidence of hydronephrosis associated with bladder carcinoma ranges from 7.2% to 54.1% [1], [2], [3].
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Mucosal Host Responses to Bacteriuria in Colonic and Ileal Neobladders
Monday, 29 January 2007
BERKELEY, CA (UroToday.com) - Reconstruction of the lower urinary tract involves incorporating an isolated segment of intestine, which is done either to replace normal tissue or to augment the existing bladder.
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UroToday.com Announces New Endourological Intervention: Left Laparoscopic Partial Nephrectomy
Sunday, 28 January 2007
BERKELEY, CA - UroToday.com announced today the addition of a new surgical video to the Urologic Surgical Interventions Corner.
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European Urology - Concomitant Carcinoma In Situ Is a Feature of Aggressive Disease in Patients With Organ-Confined TCC at Radical Cystectomy
Thursday, 18 January 2007
Volume 51, Issue 1, Pages 152-160 (January 2007) Abstract -
Objectives:
Carcinoma in situ (CIS) is a nonpapillary, high-grade, potentially aggressive, and unpredictable manifestation of transitional cell carcinoma (TCC) of the bladder. The aim of this study was to assess whether presence of concomitant CIS has a detrimental effect on cancer control after radical cystectomy.
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Is There an Indication for Frozen Section Examination of the Ureteral Margins During Cystectomy for Transitional Cell Carcinoma of the Bladder?
Wednesday, 10 January 2007
BERKELEY, CA (UroToday.com) - While ureteral frozen sections are routinely performed at the time of radical cystectomy, data from Memorial Sloan-Kettering, Johns Hopkins, and Penn have previously suggested that they may not be necessary in all patients.
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American Urological Association Names New Director of Guidelines
Wednesday, 03 January 2007
BALTIMORE, January 2007 — The American Urological Association (AUA) has announced that Heddy Hubbard, Ph.D., M.P.H., R.N., F.A.A.N. will be the new Director of Guidelines for the association. Dr. Hubbard joined the AUA on December 28, 2006.
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European Urology - Discrepancy between Clinical and Pathologic Stage: Impact on Prognosis after Radical Cystectomy
Monday, 01 January 2007
Volume 51, Issue 1, Pages 137-151 (January 2007) Abstract -
Objectives:
We compared clinical and pathologic staging in a large, contemporary, consecutive series of patients who were treated with radical cystectomy and pelvic lymphadenectomy, and determined the effect of stage discrepancy on outcomes.
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European Urology - HSP90 Expression: A New Predictive Factor for BCG Response in Stage Ta-T1 Grade 3 Bladder Tumours
Monday, 01 January 2007
Volume 51, Issue 1, Pages 161-167 (January 2007) Abstract - Objectives: Although Bacillus Calmette-Guérin (BCG) instillations are considered as the adjuvant treatment of choice for stage Ta-T1 grade G3 bladder tumours, there is no consensus for a predictive factor to assess BCG success.
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European Urology - Precystectomy Nomogram for Prediction of Advanced Bladder Cancer Stage
Friday, 29 December 2006
Volume 50, Issue 6, Pages 1254-1262 (December 2006) Abstract - Objective: To evaluate precystectomy prediction of pT and pN stages at cystectomy.
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European Urology - Partially Degraded RNA from Bladder Washing is a Suitable Sample for Studying Gene Expression Profiles in Bladder Cancer
Thursday, 28 December 2006
Volume 50, Issue 6, Pages 1347-1356 (December 2006) Abstract - Objectives: To determine the impact of different levels of RNA degradation on gene expression measurements and to ascertain if the gene expression profile obtained from bladder washing (BW) correlates to that obtained from the related bladder tumour (BT).
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European Urology - Thoughts on Delaying Cystectomy
Monday, 11 December 2006
Volume 50, Issue 6, Pages 1151-1152 (December 2006) Article Outline: The literature review of Fahmy et al. [1] reveals that the majority of studies on bladder cancer confirm that pretreatment delays are associated with worse outcome. The studies suggested a window of opportunity of less than 12 wk from diagnosis of invasive disease to radical cystectomy.
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Importance in the Management of the Prostate and Urethra in Bladder Cancer
Thursday, 07 December 2006
BETHESDA, MD (SUO 7th Annual Meeting - December 1-2, 2006:NIH) - In a session moderated by Dr. Eila Skinner, USC, Dr. Seth Lerner, Baylor spoke about the "Pathologic Assessment of Clinical Significance of Prostatic Involvement by TCC/PCA".
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Assessment and Management of High-Risk Bladder Cancer
Thursday, 07 December 2006
BETHESDA, MD (SUO 7th Annual Meeting - December 1-2, 2006:NIH) - In a session moderated by Dr. Bernard Bochner, Memorial Sloan Kettering Cancer Center, Dr. Victor Reuter spoke about "Morphologic High-Risk Tumor Characteristics".
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Bladder Cancer: How to Optimally Manage High Risk Bladder Cancer Patients
Thursday, 07 December 2006
BETHESDA, MD (SUO 7th Annual Meeting - December 1-2, 2006:NIH) - In a session moderated by Dr., Bernard Bochner, MSKCC a panel consisting of Drs. Harry Herr, Edward Messing, Dan Petrylak, and Seth Lerner had a lively discussion regarding management of high-risk bladder cancer patients.
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BJUI Mini Reviews - The Pathology of Bladder Cancer: an Update on Selected Issues
Tuesday, 05 December 2006
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BJUI Mini Reviews - Hot and Cold Technologies for Tissue Ablation in Urology
Tuesday, 05 December 2006
BERKELEY, CA (UroToday.com) - Increasingly, technology plays an important role in urology, and with this greater use comes the expected increase in regulation. Authors from the UK present a review of the physical properties of ablative technologies, evaluating efficacy and safety, and summarising guidance issued by the National Institute of Health and Clinical Excellence (NICE) where available.
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Bladder Cancer 
