European Urology - Hydronephrosis as a Prognostic Marker in Bladder Cancer in a Cystectomy-Only Series
Thursday, 01 February 2007
Volume 51, Issue 3, Pages 690-698 (March 2007)
1. Introduction
Hydronephrosis is a common finding in patients with bladder carcinoma. The incidence of hydronephrosis associated with bladder carcinoma ranges from 7.2% to 54.1% [1], [2], [3].
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Mucosal Host Responses to Bacteriuria in Colonic and Ileal Neobladders
Monday, 29 January 2007
BERKELEY, CA (UroToday.com) - Reconstruction of the lower urinary tract involves incorporating an isolated segment of intestine, which is done either to replace normal tissue or to augment the existing bladder.
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UroToday.com Announces New Endourological Intervention: Left Laparoscopic Partial Nephrectomy
Sunday, 28 January 2007
BERKELEY, CA - UroToday.com announced today the addition of a new surgical video to the Urologic Surgical Interventions Corner.
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European Urology - Concomitant Carcinoma In Situ Is a Feature of Aggressive Disease in Patients With Organ-Confined TCC at Radical Cystectomy
Thursday, 18 January 2007
Volume 51, Issue 1, Pages 152-160 (January 2007) Abstract -
Objectives:
Carcinoma in situ (CIS) is a nonpapillary, high-grade, potentially aggressive, and unpredictable manifestation of transitional cell carcinoma (TCC) of the bladder. The aim of this study was to assess whether presence of concomitant CIS has a detrimental effect on cancer control after radical cystectomy.
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Is There an Indication for Frozen Section Examination of the Ureteral Margins During Cystectomy for Transitional Cell Carcinoma of the Bladder?
Wednesday, 10 January 2007
BERKELEY, CA (UroToday.com) - While ureteral frozen sections are routinely performed at the time of radical cystectomy, data from Memorial Sloan-Kettering, Johns Hopkins, and Penn have previously suggested that they may not be necessary in all patients.
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American Urological Association Names New Director of Guidelines
Wednesday, 03 January 2007
BALTIMORE, January 2007 — The American Urological Association (AUA) has announced that Heddy Hubbard, Ph.D., M.P.H., R.N., F.A.A.N. will be the new Director of Guidelines for the association. Dr. Hubbard joined the AUA on December 28, 2006.
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European Urology - Discrepancy between Clinical and Pathologic Stage: Impact on Prognosis after Radical Cystectomy
Monday, 01 January 2007
Volume 51, Issue 1, Pages 137-151 (January 2007) Abstract -
Objectives:
We compared clinical and pathologic staging in a large, contemporary, consecutive series of patients who were treated with radical cystectomy and pelvic lymphadenectomy, and determined the effect of stage discrepancy on outcomes.
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European Urology - HSP90 Expression: A New Predictive Factor for BCG Response in Stage Ta-T1 Grade 3 Bladder Tumours
Monday, 01 January 2007
Volume 51, Issue 1, Pages 161-167 (January 2007) Abstract - Objectives: Although Bacillus Calmette-Guérin (BCG) instillations are considered as the adjuvant treatment of choice for stage Ta-T1 grade G3 bladder tumours, there is no consensus for a predictive factor to assess BCG success.
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European Urology - Precystectomy Nomogram for Prediction of Advanced Bladder Cancer Stage
Friday, 29 December 2006
Volume 50, Issue 6, Pages 1254-1262 (December 2006) Abstract - Objective: To evaluate precystectomy prediction of pT and pN stages at cystectomy.
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European Urology - Partially Degraded RNA from Bladder Washing is a Suitable Sample for Studying Gene Expression Profiles in Bladder Cancer
Thursday, 28 December 2006
Volume 50, Issue 6, Pages 1347-1356 (December 2006) Abstract - Objectives: To determine the impact of different levels of RNA degradation on gene expression measurements and to ascertain if the gene expression profile obtained from bladder washing (BW) correlates to that obtained from the related bladder tumour (BT).
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European Urology - Thoughts on Delaying Cystectomy
Monday, 11 December 2006
Volume 50, Issue 6, Pages 1151-1152 (December 2006) Article Outline: The literature review of Fahmy et al. [1] reveals that the majority of studies on bladder cancer confirm that pretreatment delays are associated with worse outcome. The studies suggested a window of opportunity of less than 12 wk from diagnosis of invasive disease to radical cystectomy.
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Importance in the Management of the Prostate and Urethra in Bladder Cancer
Thursday, 07 December 2006
BETHESDA, MD (SUO 7th Annual Meeting - December 1-2, 2006:NIH) - In a session moderated by Dr. Eila Skinner, USC, Dr. Seth Lerner, Baylor spoke about the "Pathologic Assessment of Clinical Significance of Prostatic Involvement by TCC/PCA".
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Assessment and Management of High-Risk Bladder Cancer
Thursday, 07 December 2006
BETHESDA, MD (SUO 7th Annual Meeting - December 1-2, 2006:NIH) - In a session moderated by Dr. Bernard Bochner, Memorial Sloan Kettering Cancer Center, Dr. Victor Reuter spoke about "Morphologic High-Risk Tumor Characteristics".
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Bladder Cancer: How to Optimally Manage High Risk Bladder Cancer Patients
Thursday, 07 December 2006
BETHESDA, MD (SUO 7th Annual Meeting - December 1-2, 2006:NIH) - In a session moderated by Dr., Bernard Bochner, MSKCC a panel consisting of Drs. Harry Herr, Edward Messing, Dan Petrylak, and Seth Lerner had a lively discussion regarding management of high-risk bladder cancer patients.
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BJUI Mini Reviews - The Pathology of Bladder Cancer: an Update on Selected Issues
Tuesday, 05 December 2006
BERKELEY, CA (UroToday.com) - The Uropathology Working Group (European Society of Pathology) and the European Society of Uropathology met in Palermo, on 18 June 2005, for a workshop held during the 78th Congress of the Italian Society of Urology. In this paper we summarize the discussions and conclusions of the bladder tumour subcommittee.
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BJUI Mini Reviews - Diagnostic Tests Used in the Investigation of Adult Haematuria: a Systematic Review
Tuesday, 05 December 2006
BERKELEY, CA (UroToday.com) - Haematuria can be a symptom of serious underlying pathology (e.g. urological malignancy), but also has many benign causes (e.g. vigorous exercise).
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BJUI Mini Reviews - Hot and Cold Technologies for Tissue Ablation in Urology
Tuesday, 05 December 2006
BERKELEY, CA (UroToday.com) - Increasingly, technology plays an important role in urology, and with this greater use comes the expected increase in regulation. Authors from the UK present a review of the physical properties of ablative technologies, evaluating efficacy and safety, and summarising guidance issued by the National Institute of Health and Clinical Excellence (NICE) where available.
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European Urology - Radical Cystectomy – Often Too Late? Yes, But …
Friday, 01 December 2006
Volume 50, Issue 6, Pages 1129-1138 (December 2006)Article Outline - The editors of European Urology elected to reprint this manuscript, which was initially published almost 20 yr ago and continues to contain important messages. Not only was the Mainz group one of the initiators advocating radical cystectomy as the optimal treatment for invasive bladder cancer, but they also made the following important points that are still true to this day.
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European Urology - Delay in the Surgical Treatment of Bladder Cancer and Survival: Systematic Review of the Literature
Friday, 01 December 2006
Volume 50, Issue 6, Pages 1176-1182 (December 2006) 1. Introduction: Bladder cancer is the sixth most common noncutaneous cancer in Canada. It is the 8th most common cause of cancer death in males and the 13th in females [1].
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European Urology - Supra-ampullar Cystectomy and Ileal Neobladder
Friday, 01 December 2006
Volume 50, Issue 6, Pages 1223-1233 (December 2006) Abstract - Objective: This article describes both the open and laparoscopic operative techniques of supra-ampullar cystectomy (SAC).
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Intraoperative Frozen Section Analysis of Ureteral Margins during Cystectomy
Monday, 20 November 2006
BERKELEY, CA (UroToday.com) - At the time of cystectomy many urologists send distal ureteral margins for frozen section analysis.
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Use of Personal Permanent Hair Dye is Not Linked to Bladder Cancer Risk
Tuesday, 14 November 2006
BERKELEY, CA (UroToday.com) - An occupational exposure to hair dyes by hairdressers and barbers is shown to increase their bladder cancer risk. Hair dyes contain small amounts of aromatic amines, which are shown to be carcinogenic in animals.
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Matritech Promotes Bladder Cancer Awareness November 12-18 and Encourages People at Risk for the Cancer to be Tested
Thursday, 09 November 2006
Newton, MA (November 9, 2006) – Matritech, Inc. (Amex: MZT) a leading developer of protein-based diagnostic products for the early detection of cancer has joined forces for the second consecutive year with leading urologists, urology nurses, community based healthcare providers, bladder cancer patient advocates, and firefighters to raise awareness of bladder cancer during National Bladder Health Awareness Week, November 12-18, 2006, and urges people who are at risk for bladder cancer to ask their doctor to be tested for the cancer.
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Bladder Cancer Awareness Week
Wednesday, 08 November 2006
Early Detection Saves Lives - According to the National Cancer Institute, the prevalence of bladder cancer in the United States has surpassed that of lung cancer.
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Society of Urologic Nurses and Associates Launches Initiative to Educate Public about Bladder Health
Tuesday, 31 October 2006
PITMAN, NJ (Press Release) - A free slide presentation is now available for urologic health care providers to bring to local communities. Cancer warning signs, infections, and related topics are discussed.
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A First for Rhode Island Firefighters – Bladder Cancer Screening is Underway in Five Communities with the NMP22® BladderChek® Test
Wednesday, 25 October 2006
NEWTON, MA (Press Release) - In a first for Rhode Island, firefighters in Little Compton, Tiverton, Portsmouth, Middletown, and Jamestown are being offered free screening for bladder cancer in a voluntary program paid for and sponsored by their local state representatives.
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European Urology - Plasmacytoid Urothelial Carcinoma of the Urinary Bladder: Report of Seven New Cases
Wednesday, 25 October 2006
Volume 50, Issue 5, Pages 1111-1114 (November 2006) Abstract - Introduction: Plasmacytoid urothelial carcinoma (PUC) is a rare tumor of the urinary bladder. Its clinical and histopathological features have not been well characterized.
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Improved Detection of Bladder Cancer in Diagnosis and Surveillance Patients Using a Point-of-Care Proteomic Assay
Wednesday, 11 October 2006
PROVIDENCE, RI (Press Release) - October 2006 - During a recent medical presentation at the American Urological Association New England Section meeting on Sept. 29, the NMP22 Clinical Investigation Group further described clinical utility of the NMP22® BladderChek® Test combined with cystoscopy as a "molecular" staging and grading of a bladder malignancy prior to a biopsy.
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European Urology - Foreseeing Cancer Metastases
Monday, 02 October 2006
Volume 50, Issue 4, Pages 648-649 (October 2006) Metastatic potential reveals the true nature of cancer. In more advanced bladder cancer metastases occur during disease follow-up in >50% of cases, despite extensive local treatment.
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European Urology - Elevated Microsatellite Instability at Selected Tetranucleotide Repeats does not Correlate with Clinicopathologic Features of Bladder Cancer
Monday, 02 October 2006
Volume 50, Issue 4, Pages 770-776 (October 2006) Abstract -
Introduction:
The aim of the present study was to evaluate whether elevated microsatellite instability (MSI) at selected tetranucleotide repeats (EMAST) is associated with clinicopathologic and molecular parameters in urinary bladder cancer (BC).
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European Urology - Focal S100A4 Protein Expression Is an Independent Predictor of Development of Metastatic Disease in Cystectomized Bladder Cancer Patients
Monday, 02 October 2006
Volume 50, Issue 4, Pages 777-785 (October 2006) 1. IntroductionSubclinical spread of cancer cells, present at the time of diagnosis and definite treatment, constitutes the biggest threat to patients with seemingly localized muscle-invasive bladder cancer. Despite radical cystectomy, offering excellent local control, around 30–50% of these patients still succumb to distant metastases.
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European Urology - Molecular and Immunohistochemical Analysis of the Prognostic Value of Cell-Cycle Regulators in Urothelial Neoplasms of the Bladder
Thursday, 21 September 2006
Volume 50, Issue 3, Pages 506-515 (September 2006)
Abstract -
Objective:
To evaluate the prognostic and predictive value of molecular and immunohistochemical markers related to cell-cycle control in terms of recurrence, progression, and survival in urothelial neoplasms of the bladder (UNB).
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European Urology - Should Bladder Biopsies be Performed Routinely after Bacillus Calmette-Guérin Treatment for High-Risk Superficial Transitional Cell Cancer of the Bladder?
Thursday, 21 September 2006
Volume 50, Issue 3, Pages 516-520 (September 2006) Abstract -
Objective:
After endoscopic resection of high-grade superficial urothelial neoplasms (Ta, T1 or Tis), adjuvant bacillus Calmette-Guérin (BCG) therapy is performed routinely to avoid recurrence and/or progression. Vesical biopsies often are performed to assess the efficacy of treatment. The aim of our study was to evaluate the usefulness of these biopsies.
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Long-Term Effects of Ileal Conduit Diversion on Upper Urinary Tract in Bladder Cancer Examined
Tuesday, 19 September 2006
BERKELEY, CA (UroToday.com) - Ileal conduit urinary diversion, popularized by Bricker, has been applied for a half a century as the most standardized form of urinary diversion.
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Masterclass for Urologists on Medical Tumor Treatment Held in Barcelona
Wednesday, 13 September 2006
ARNHEM, THE NETHERLANDS (Press Release) - September 2006 - A masterclass for practicing urologists who are involved in cancer care of urological patients is organized from 29 September to 1 October in Hotel Fira Palace in Barcelona, Spain.
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European Society for Urological Research to Host Congress in Malmo, Sweden
Friday, 08 September 2006
ARNHEM, THE NETHERLANDS (Press Release) - September 2006 - The European society for urological research (ESUR) will host its 17th congress in Malmö, Sweden from 14 to 16 September.
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The Role for Screening High Risk Patients for Bladder Cancer
Thursday, 07 September 2006
BERKELEY, CA (UroToday.com) - Bladder cancer is a common disease with over 60,000 new cases predicted for this year and an estimated prevalence of approximately 500,000 cases. Routine programs for bladder cancer screening have not been established because of the somewhat low incidence of disease in general populations.
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Bladder Cancer Screening Underway in Communities across the Country Using the NMP22(R) BladderChek(R) Test
Wednesday, 06 September 2006
NEWTON, Mass.--(BUSINESS WIRE)--Sept. 6, 2006-- Report in American Cancer Society Journal Shows Matritech's NMP22(R) BladderChek(R) Test Can Save Lives and Reduce Expense by Screening High Risk Groups for Bladder Cancer.
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European Urology - Improving Efficacy of Intravesical Chemotherapy
Thursday, 03 August 2006
Gasión JPB, Cruz JFJEuropean UrologyAugust 2006 (Vol. 50, Issue 2, Pages 225-234)Published online 6 June 2006
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European Urology - Gene Expression in Normal Urothelium Depends on Location within the Bladder: A Possible Link to Bladder Carcinogenesis
Wednesday, 02 August 2006
Doherty SC, McKeown SR, Lopez JA, Walsh IK, McKelvey-Martin VJEuropean UrologyAugust 2006 (Vol. 50, Issue 2, Pages 290-301) Published online 25 January 2006
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New Study in Journal of Urology Shows UroVysion™ DNA Test Superior to Standard Cytology in Diagnosing Bladder Cancer in At-risk Patients
Monday, 24 July 2006
Study Points to the High Sensitivity of UroVysion and its Clinical Benefits
Des Plaines, Illinois, July 20, 2006 - A study published in the July 2006 edition of Journal of Urology has shown that UroVysion™, a DNA-based urine test that detects important genetic changes in bladder cells, has almost twice the sensitivity of conventional urine cytology tests, the current gold standard, as an aid for the initial diagnosis of bladder cancer in patients with hematuria (blood in urine) suspected of having bladder cancer.
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American Cancer Society Journal Article Reports Screening High Risk Populations for Bladder Cancer is Cost Effective; Matritech's NMP22(R) BladderChek(R) Test Can Save Lives and Reduce Expense Screening High Risk Populations for Bladder Cancer
Monday, 24 July 2006
NEWTON, Mass.--(BUSINESS WIRE)--July 24, 2006--An article published in an early online view of the American Cancer Society's journal Cancer reports that screening for bladder cancer in high risk populations can save lives and reduce overall medical expenses.
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Intravesical Gemcitabine Demonstrates Activity in Bladder Cancer Patients Who Fail BCG
Tuesday, 18 July 2006
BERKELEY, CA (UroToday.com) - Patients who fail BCG and present with tumor recurrence will either; undergo salvage repeat BCG, BCG combined with interferon-alpha, both which demonstrate a 40-50% success rate or they proceed to cystectomy.
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Urologic Professionals to Learn Latest Practice Advances at Society of Urologic Nurses and Associates Annual Conference
Monday, 10 July 2006
Pitman, NJ - The Society of Urologic Nurses and Associates' (SUNA) will hold its 2006 Annual Conference in Kansas City, MO, October 27-30, 2006, at the Hyatt Regency Crown Center.
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Association Between Marijuana Use And The Incidence Of Transitional Cell Carcinoma Suggested
Tuesday, 27 June 2006
BERKELEY, CA (UroToday.com) - Like tobacco smoking, marijuana smoking has been implicated as a causative factor in tumors of the head and neck and of the lung. The marijuana smokers in whom these tumors occur are usually much younger than the tobacco smokers who are the usual victims of these malignancies. A question remains as to whether transitional cell carcinoma (TCCA), highly linked to tobacco use, can also be linked to marijuana use and if the cancers seen in marijuana smokers are similar to those seen in tobacco users.
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Adjuvant Mitomycin C Does Not Compensate For An Inadequate Resection In T1 Bladder Cancer: More Evidence In Favor Of A Repeat TUR
Wednesday, 21 June 2006
BERKELEY, CA (UroToday.com) - Due to the measurable incidence of residual disease after TUR (approaching 35%) and pathologic understaging, repeat TUR is recommended for all patients with clinical stage T1 disease. Does using adjuvant intravesical mitomycin C obviate the need for a repeat TUR?
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Patients With No Residual Cancer In The Cystectomy Specimen (pT0 Disease): Are They Cured Of Bladder Cancer?
Friday, 16 June 2006
BERKELEY, CA (UroToday.com) - In the May 2006 issue of the Journal of Urology, Palapattu and colleagues from the Bladder Cancer Research Consortium reviewed the records of 888 consecutive, evaluable patients who underwent radical cystectomy for TCC at 3 institutions over a 19 year period. Cystectomy was performed for CIS in 5 (9%), Ta in 2 (4%), T1 in 18 (32%), T2 in 29 (52%) and T3 in 2 (4%). Fifty nine patients were identified without carcinoma in the surgical specimen (7%). Two of these patients (3%) had evidence of lymph node metastasis.
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Octagenarians With Superficial Bladder Cancer Exhibit A Decreased Response To Intravesical Immunotherapy
Thursday, 15 June 2006
BERKELEY, CA (UroToday.com) - In the May issue of the Journal of Urology, Joudi and colleagues from Iowa City report data from a national phase II multicenter trial of intravesical BCG plus interferon-alpha. The cohort consisted of 1,106 patients treated with 81 mg of BCG plus 50 MU IFN-alpha if BCG naïve, one-third of the BCG dose with 50 MU IFN-alpha if previously treated with BCG, or one-tenth the BCG dose with 100 MU IFN-alpha if previously intolerant to BCG. The inclusion criteria consisted of patients with all types of superficial bladder cancer, with or without CIS, and with or without prior intravesical chemotherapy or immunotherapy.
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Comparative Study Of Ileocecal vs. Ileal Neobladders In Radical Cystectomy Patients
Monday, 12 June 2006
BERKELEY, CA (UroToday.com) - The use of orthotopic urinary diversion has gained increasing popularity in the past 20 years. Intestinal options for neobladders include ileocecal and ileal segments. The choice of intestinal segment has both functional and metabolic implications. In the April issue of the BJU International, Dr. Khafagy and associates from the National Cancer Institute, Cairo, Egypt report a comparative study using either ileocecal or ileal neobladders.
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AUA 2006 - Studies Presented at American Urological Association Expand the Role of the NMP22® BladderChek® Test
Thursday, 25 May 2006
Improves Bladder Cancer Detection to 99% - Aiding the Earlier Detection of Cancer
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Bladder Cancer 
