European Urology - Urethral Compression for the Treatment of Postprostatectomy Urinary Incontinence: Is History Repeating Itself?
Thursday, 01 February 2007
Volume 51, Issue 2, Pages 304-305 (February 2007) After more than a century since the first prostatectomy was described by Young, the debate continues regarding the optimal treatment of postprostatectomy incontinence (PPI). PPI remains a devastating and frustrating complication for both patients and urologists alike.
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European Urology - Prostate Cancer in the Swedish Section of ERSPC—Evidence for Less Metastases at Diagnosis but not for Mortality Reduction
Sunday, 11 February 2007
Volume 51, Issue 3, Pages 588-590 (March 2007)
In this issue of the journal, Aus et al. [1] report on the risk of being diagnosed with advanced (metastatic) prostate cancer among men in the Swedish randomised screening study, which is part of the European Randomized Study of Screening for Prostate Cancer (ERSPC) [2], [3].
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European Urology - Will Robotic Surgery Become the Gold Standard for Radical Prostatectomy?
Monday, 01 January 2007
Volume 51, Issue 1, Pages 9-11 (January 2007)
1. The worldwide spread of robotic surgery
The robotic assistance by the da Vinci surgical system (Intuitive Surgical, Sunnyvale, CA) offers to surgeons a sophisticated tool to perform complex laparoscopic surgery. With a global cost of approximatively 1 million euros, the da Vinci robot was developed for the military and sold to private industry.
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European Urology - The Prostate Cancer Prevention Trial and Its Messages
Monday, 01 January 2007
Volume 51, Issue 1, Pages 6-8 (January 2007) The discovery of prostate-specific antigen (PSA) almost two decades ago and its introduction into clinical practice has revolutionised the management of prostate cancer [1].
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European Urology - Testosterone and Prostate Cancer
Thursday, 01 February 2007
Volume 51, Issue 2, Pages 293-295 (February 2007) The role of testosterone in the pathophysiology of prostate cancer (pCA) remains elusive and the conundrum is yet to be solved. After Huggins and Hodges proved that testosterone reduction by castration or oestrogen treatment caused regression of metastatic disease, the detrimental effect of testosterone administration in patients at risk of or with pCA was inferred [1].
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European Urology - Advanced Prostate Cancer: At Last a Role for Medical Oncologists
Monday, 01 January 2007
Volume 51, Issue 1, Pages 4-5 (January 2007) “What is more exciting? The activity of docetaxel in early prostate cancer or the successful collaboration between urologists and medical oncologists to complete a study in early prostate cancer?” The title and the content of this editorial paper by Michael Carducci, published in May 2005 [1], always aroused my enthusiasm and agreement.
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European Urology - Do We Need the Final Results of the ERSPC Trial?
Thursday, 01 February 2007
Volume 51, Issue 2, Pages 291-292 (February 2007) The oncologic community eagerly awaits the final results of the two important international screening studies for prostate cancer (Prostate, Lung Colorectal and Ovary [PLCO] and European Randomized Study of Screening for Prostate Cancer [ERSPC]). In the report by de Vries et al. in the current issue of the journal [1], the investigators of the ERSPC trial publish for the first time results regarding overall and disease-specific survival in the screening arm of the Rotterdam section of the trial compared to historical controls.
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European Urology - Prostatic Fascial Anatomy and Positive Surgical Margins in Laparoscopic Radical Prostatectomy
Monday, 11 December 2006
Volume 51, Issue 3, Pages 598-600 (March 2007)
The magnification obtained with laparoscopy has allowed urologists to rediscover prostatic anatomy. The distinction between intrafascial, interfascial, and extrafascial dissection can be made only with the increased visual capability that is obtained with the laparoscopic approach.
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European Urology - Preoperative and Intraoperative Risk Factors for Side-Specific Positive Surgical Margins in Laparoscopic Radical Prostatectomy for Prostate Cancer
Thursday, 01 March 2007
Volume 51, Issue 3, Pages 764-771 (March 2007)
1. Introduction:
Surgical margin (SM) status is the only pathologic variable that can be objectively measured to determine complete tumour resection
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European Urology - Robotic-Assisted Laparoscopic Prostatectomy: Functional and Pathologic Outcomes with Interfascial Nerve Preservation
Thursday, 01 March 2007
Volume 51, Issue 3, Pages 755-763 (March 2007)
Abstract -
Introduction:
Robotic-assisted laparoscopic radical prostatectomy (RLRP) is increasingly becoming an alternative to open and laparoscopic radical prostatectomy in the treatment of localized prostate cancer.
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European Urology - Clinically Overt Venous Thromboembolism after Urologic Cancer Surgery: Results from the @RISTOS Study
Monday, 01 January 2007
Volume 51, Issue 1, Pages 130-136 (January 2007) Abstract - Objective: Incidence of venous thromboembolism (VTE) and need for thromboprophylaxis in urologic surgery have received little attention since only one randomised study has addressed this issue in the last 20 yr.
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European Urology - Radical Prostatectomy in Austria: A Nationwide Analysis of 16,524 Cases
Thursday, 01 March 2007
Volume 51, Issue 3, Pages 684-689 (March 2007)
Abstract -
Objectives:
To analyse demographics and outcome of radical prostatectomy (RPE) in Austria in a nationwide series.
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European Urology - Outcome of Surgery for Clinical Unilateral T3a Prostate Cancer: A Single-Institution Experience
Monday, 01 January 2007
Volume 51, Issue 1, Pages 121-129 (January 2007) Abstract -
Objectives:
The optimal management of locally advanced prostate cancer (cT3) is still a matter of debate. The objective of this study is to present 10-year outcomes of radical prostatectomy (RP) in unilateral cT3a disease.
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European Urology - Optimal Sampling Sites for Repeat Prostate Biopsy: A Recursive Partitioning Analysis of Three-Dimensional 26-Core Systematic Biopsy
Thursday, 01 March 2007
Volume 51, Issue 3, Pages 675-683 (March 2007)
Abstract -
Objectives:
To explore an optimal combination of sampling sites to detect prostate cancer in a repeat biopsy setting.
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European Urology - A Nomogram for Staging of Exclusive Nonobturator Lymph Node Metastases in Men with Localized Prostate Cancer
Monday, 01 January 2007
Volume 51, Issue 1, Pages 112-120 (January 2007) Abstract -
Objectives:
Some patients with localized prostate cancer are at risk of nonobturator lymph node invasion (NOLNI) and may require an extended pelvic lymph node dissection (ePLND). We explored the rate of exclusive NOLNI and developed a nomogram to predict it.
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European Urology - A Pretreatment Table for the Prediction of Final Histopathology after Radical Prostatectomy in Clinical Unilateral T3a Prostate Cancer
Thursday, 01 February 2007
Volume 51, Issue 2, Pages 388-396 (February 2007)Abstract -Objectives: Partin tables are the most widely used tool to predict histopathologic stage after radical prostatectomy (RP) in organ-confined tumors. Such a predictive table in clinical T3 disease is still lacking.
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European Urology - Prognostic Value of CpG Island Hypermethylation at PTGS2, RAR-beta, EDNRB, and Other Gene Loci in Patients Undergoing Radical Prostatectomy
Thursday, 01 March 2007
Volume 51, Issue 3, Pages 665-674 (March 2007)
Abstract -
Objectives:
To evaluate CpG island hypermethylation in a set of candidate genes in prostate cancer (pCA) and its relationship to clinicopathologic parameters and a nomogram predicting prostate-specific antigen (PSA) recurrence after radical prostatectomy.
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European Urology - Nerve Distribution along the Prostatic Capsule
Monday, 01 January 2007
Volume 51, Issue 1, Pages 105-111 (January 2007) Abstract - Objectives: Recent literature describes indications for a more-complex course of fibres of the neurovascular bundle (NVB), despite the widely held assumption that it is gathered at the rectolateral side of the prostate. The objective of this study therefore was to determine the typical pattern of nerve distribution along the prostatic capsule.
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European Urology - Control of Prostate Cancer by Transrectal HIFU in 227 Patients
Thursday, 01 February 2007
Volume 51, Issue 2, Pages 381-387 (February 2007) Abstract -Purpose: To evaluate the results of high-intensity focused ultrasound (HIFU) treatment of localized prostate cancer with reference to disease-related prognostic factors.
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European Urology - Prostate Cancer Screening Decreases the Absolute Risk of Being Diagnosed with Advanced Prostate Cancer—Results from a Prospective, Population-Based Randomized Controlled Trial
Thursday, 15 February 2007
Volume 51, Issue 3, Pages 659-664 (March 2007)
1. Introduction
The trends in mortality from prostate cancer vary widely from country to country across the industrialized world [1].
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European Urology - Different Types of Atrophy in the Prostate With and Without Adenocarcinoma
Monday, 01 January 2007
Volume 51, Issue 1, Pages 98-104 (January 2007) Abstract -
Objectives:
The purpose of this study was to evaluate, according to a classification proposed by a working group, the extent and type of atrophy lesions in radical prostatectomy specimens obtained from patients with prostatic carcinoma and benign prostatic hyperplasia (BPH), and to compare the prevalence and types of atrophy between two investigated groups.
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European Urology - The Clinical Potential of Pretreatment Serum Testosterone Level to Improve the Efficiency of Prostate Cancer Screening
Thursday, 01 February 2007
Volume 51, Issue 2, Pages 375-380 (February 2007)1. Introduction: Prostate cancer is the result of a complex and unclear interaction between ageing, genetic factors, hormones, growth factors, and environment.
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European Urology - Nerve-Sparing Open Radical Retropubic Prostatectomy
Monday, 01 January 2007
Volume 51, Issue 1, Pages 90-97 (January 2007) Abstract -
Introduction:
In recent years, the surgical technique for open radical prostatectomy has evolved and increasing attention is paid to preserving anatomic structures and the impact on outcome and quality of life.
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European Urology - Overall and Disease-Specific Survival of Patients with Screen-Detected Prostate Cancer in the European Randomized Study of Screening for Prostate Cancer, Section Rotterdam
Thursday, 01 February 2007
Volume 51, Issue 2, Pages 366-374 (February 2007) 1. Introduction: Prostate cancer (pCA), unlike most other malignant diseases, has a protracted natural course in the majority of cases. Treatment after an early diagnosis of prostate cancer (pCA), facilitated by screening, could possibly improve disease-specific survival [1].
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European Urology - Vattikuti Institute Prostatectomy: Contemporary Technique and Analysis of Results
Thursday, 15 February 2007
Volume 51, Issue 3, Pages 648-658 (March 2007)
Abstract -
Objectives:
Contemporary techniques of radical prostatectomy achieve excellent oncologic outcomes; erectile dysfunction is the most common adverse effect.
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European Urology - Anatomical Landmarks of Radical Prostatecomy
Thursday, 15 February 2007
Volume 51, Issue 3, Pages 629-639 (March 2007)
Abstract -
Introduction:
In the present study, we review current literature and based on our experience, we present the anatomical landmarks of open and laparoscopic/endoscopic radical prostatectomy.
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European Urology - Evidence from Robot-Assisted Laparoscopic Radical Prostatectomy: A Systematic Review
Monday, 01 January 2007
Volume 51, Issue 1, Pages 45-56 (January 2007) 1. Introduction: Although first performed in 1992 [1], laparoscopic radical prostatectomy (LRP) received little attention until the first reports from France. In Europe, the first LRP was performed by Richard Gaston in September 1997. In the following years, Guillonneau and Vallancien standardised the Montsouris technique and facilitated the spread of LRP to several European centres [2], [3], [4], [5], [6], [7].
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European Urology - Implications of Prostate-Specific Antigen Doubling Time as Indicator of Failure after Surgery or Radiation Therapy for Prostate Cancer
Tuesday, 13 February 2007
Volume 51, Issue 3, Pages 605-613 (March 2007)
Abstract -
Objectives:
To review the methodology of PSA doubling time (PSA DT) calculations and the implications of PSA DT for the follow-up of prostate cancer patients curatively treated with surgery or radiation therapy.
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European Urology - Looking Back at PCPT: Looking Forward to New Paradigms in Prostate Cancer Screening and Prevention
Monday, 01 January 2007
Volume 51, Issue 1, Pages 27-33 (January 2007) 1. The case for prevention - Prostate cancer is the most common noncutaneous malignancy in men [1]. Despite numerous advances in the early detection and treatment of the disease, approximately 27,350 men will die of the disease in 2006 [1].
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European Urology - Antiandrogens in the Treatment of Prostate Cancer
Thursday, 01 February 2007
Volume 51, Issue 2, Pages 306-314 (February 2007) Abstract - Objectives: To give an overview on the contemporary role of antiandrogens in prostate cancer treatment.
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European Urology - Current Indications for Chemotherapy in Prostate Cancer Patients
Monday, 01 January 2007
Volume 51, Issue 1, Pages 17-26 (January 2007) 1. Introduction: Prostate cancer is the most common lethal malignancy diagnosed in American men and the third leading cause of male cancer mortality.
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