ANAHEIM, CA (UroToday.com) - Johnson and colleagues from Madison, Wisconsin reported that high dose zinc supplementation actually increased hospitalizations for urinary tract infections and urinary lithiasis compared to placebo in the Age-Related Eye Disease Study of 3640 patients with macular degeneration.

(ABST [59]) High-Dose Zinc Increases Hospital Admissions Due to Genitourinary Complications

On Sunday, Morrisroe and co-workers from Pittsburgh showed experimental evidence that green tea protects bladder cells from hydrogen peroxide-induced inflammation in normal and malignant bladder urothelial cells in vitro. Green tea extract and two major green tea extract catechin components were tested. They suggest that herbal supplementation with catechin compounds may be a viable therapeutic modality for the treatment of various inflammatory or injury-induced bladder conditions such as interstitial cystitis.

(ABST [299]) Green Tea Protects Bladder Cells from Hydrogen Peroxide-Induced Inflammation: Potential of Herbal Agents to Treat Inflammatory Bladder Diseases

Zhang, Guo, and Keay from Baltimore found that expression of claudin 1, 4,8, and 12 proteins are significantly decreased in cells grown from interstitial cystitis patients as compared to matched controls of normal bladders. They postulate that this may lead to the leakiness of the bladder epithelial barrier in interstitial cystitis.

(ABST [297]) Decreased Expression of Claudins 1, 4 and 8 in Bladder Epithelial Cell Explants from Interstitial Cystitis Patients as Compared to Normal Controls

UroToday.com Full Conference Reports

Written by Philip M. Hanno, MD, a Contributing Editor with UroToday.

Please log-in or register in order to submit comments.

Powered by AkoComment!