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ICS 2006 - ABST[153] ARE DETRUSOR OVERACTIVITY AND “INCREASED BLADDER SENSATION” BOTH PART OF THE SAME SPECTRUM OF BLADDER DYSFUNCTION? Haylen B1, Chetty N2, Logan V 3, Schulz S3, Verity L3, Zhou J4, Law M5 1. ST VINCENTS CLINIC, SYDNEY. AUSTRALIA., 2. ST VINCENTS HOSPITAL, SYDNEY. AUSTRALIA., 3. ST VINCENTS CLINIC, SYDNEY. AUSTRALIA, 4. UNIVERSITY OF NSW, SYDNEY. AUSTRALIA., 5. UNIVERSITY OF NSW, SYDNEY. AUSTRALIA Hypothesis / aims of study Historically, the diagnosis of “sensory urgency” was discontinued as a term by the ICS in 2003. This followed 25 years of continuous clinical and academic usage. It had been suggested that “sensory urgency” was an early form of detrusor overactivity (DO). The equivalent current term would appear to be “increased bladder sensation” (IBS). The study aims to compare the clinical and urodynamic associations of IBS and DO. Study design, materials and methods 592 women attending for an initial urogynaecological / urodynamic assessment took part in this prospective study. In addition to a full clinical assessment, all women underwent free uroflowmetry, RUV measurement (by vaginal ultrasound [1]) and multichannel filling and voiding cystometry. Data was separated into those having (i) neither IBS or DO); (ii) IBS (iii) DO. Apart from prevalence figures, comparative associations were sought for (iii) age; (iv) parity; (v) presenting symptoms; (vi) presence of at least 1 documented urinary tract infection (UTI) in the previous 12 months; (vii) 2 or more (recurrent) documented UTI in the previous 12 months; (viii) prior hysterectomy; (ix) prior continence surgery (x) menopause (xi) menopause and HRT use; (xii) sign of clinical stress leakage; (xiii) retroverted uterus; (xiv) anterior vaginal prolapse; (xv) uterine prolapse; (xvi) posterior vaginal prolapse; (xvii) apical vaginal prolapse; (xviii, xix) maximum, average urine flow rate (MUFR, AUFR) centiles, Liverpool Nomograms [2]; (xx) median residual urine volume (RUV) mls; (xxi,xxii) voiding difficulty: VD1,VD2 (MUFR, AUFR under 10th centile Liverpool Nomogram and/or RUV >30mls); (xxiii) diagnosis of urodynamic stress incontinence (USI); (xxiv) diagnosis of uterine and/or vaginal prolapse (grade >0). Results: Interpretation of results The clinical and urodynamic profiles of IBS and DO are very similar. Women with either IBS or DO are less likely to have symptoms, signs or diagnoses of stress incontinence (USI) or prolapse than women with neither IBS or DO. Concluding message IBS and DO appear to be part of the same spectrum of bladder dysfunction. The difference in median age may point to IBS being an earlier form of DO. 1: Brit J Urol , 1989,64:347-349 2: Brit J Urol, 1989, 64:21-30
FUNDING: NONE DISCLOSURES: NONE HUMAN SUBJECTS: This study did not need ethical approval because Ehthics committee approval was not required. but followed the Declaration of Helsinki Informed consent was obtained from the patients.
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