Horninger W.¹, Pelzer A.E.¹, Bektic J.¹, Achleitner R.¹, Frauscher F.², Pallwein L.², Schafer G.³, Klocker H.¹, Bartsch G.¹

Presented on March, 22 2007

INTRODUCTION & OBJECTIVES: To evaluate the complication rates of TRUS guided prostate biopsies in a healthy screening population.

MATERIAL & METHODS: Between January 1993 and October 1995 sextant biopsies, between November 1995 and February 2000 10 systematic biopsies and since then 5 additional targeted biopsies of the prostate were performed. All screening volunteers received oral proplylactic antibiotic therapy (ciprofloxacin 250 mg twice daily) starting one day before the procedure. Complications were categorized in minor complications (haematuria >1 day, hematospermia, rectal bleeding <2 days) and major complications (prostatitis, epididymitits, fever > 38°C, rectal bleeding >2 days and/or requiring surgical intervention, urinary retention, other complications requiring hospitalisation). Complication rates were assessed by a physician either in a personal interview or by phone.

RESULTS: 7074 biopsies were performed in 5153 men. Haematuria and haemospermia were the most frequent reported side effects occurring in 13.8% and 35.8%, respectively. Further data are shown in the table below:
 

CONCLUSIONS: Haematuria and haemospermia are frequently reported, however, they cause minimal discomfort and require no additional treatment; major complications requiring hospitalisation were rare. According to these data TRUS-guided prostate biopsy is a safe procedure in a healthy screening population.

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