VIPUL PATEL, ADAM MUES
OHIO STATE UNIVERSITY, COLUMBUS OHIO

Introduction: We report our biochemical recurrence data for patients who are at a minimum of one-year post robot-assisted prostatectomy (RAP).

Method: We retrospectively assessed 354 patients that underwent RAP and
were at least 1 year out post surgery. Histopathologic outcomes were determined by the TNM stage, Gleason grade, and margin status. Biochemical recurrence was defined as an increase in PSA level of greater than 0.2. Patients were followed with PSA values every 3 months following surgery for recurrence.

Result: 354 patients have follow up of greater than one year (mean 23 months). The positive margin rate for the series was 10.7% and PSA recurrence was seen in 15 (4.2%) patients. The first 100 patients had six recurrences. In Gleason grades 7 (1), 8 (1), and 9 (4) and pathologic stages T3a (2), T3b (1), T3c (1), and T4 (2). The second 100 cases had three recurrences with Gleason's of 7 (2), and 9 (1), all T3b. In the third 100 Gleason's 7 (1), 9 (3). Recurrence was found in T3b (2) and T4 (2). In the last 54 two patients with Gleason's 7 and T4 disease had biochemical recurrence.

Conclusion: At this time PSA recurrence has only been seen for Gleason's
grade 7 and above, and with extensive (T3a), T3b or T4 disease. We have not
seen any recurrence with organ confined T2 disease or focal T3a. Long-term
follow up is necessary for adequate comparison to the other approaches.

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